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Purified anti-human CD245 (p220/240) Antibody

Pricing & Availability
Clone
DY12 (See other available formats)
Regulatory Status
RUO
Other Names
P220/240, DY12, DY35
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
DY12_Pure_081908.jpg
Human peripheral blood lymphocytes stained with purified DY12, followed by biotinylated anti-mouse IgG and Sav-PE
  • DY12_Pure_081908.jpg
    Human peripheral blood lymphocytes stained with purified DY12, followed by biotinylated anti-mouse IgG and Sav-PE
Cat # Size Price Save
334402 100 µg ¥28,380
Description

CD245 is a 220-250 kD transmembrane glycoprotein, also known as p220/240, DY12 or DY35. It is expressed on peripheral blood lymphocytes, monocytes, granulocytes, and platelets. The expression level of CD245 on lymphocytes can be upregulated after 3-7 days stimulation with PHA. It has been reported that CD245 is involved in signal transduction and costimulation of T and NK cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_1186022 (BioLegend Cat. No. 334402)

Antigen Details

Distribution

Blood lymphocytes, monocytes and granulocytes

Function
Signal transduction and costimulation
Cell Type
Granulocytes, Lymphocytes, Monocytes
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. H. Zola et al. Eds. 2007. Leukocyte and Stromal Cell Molecule:The CD Markers. WILEY-LISS:A John Wiley & Sons Inc, Publication

Gene ID
4863 View all products for this Gene ID
UniProt
View information about CD245 on UniProt.org
Go To Top Version: 2    Revision Date: 08/25/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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