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Purified anti-human CD92 Antibody

Pricing & Availability
Clone
VIM15b (See other available formats)
Regulatory Status
RUO
Workshop
HCDM listed
Other Names
CD92, CDw92, CTL1, SLC44A1
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
VIM15b_PURE_CD92_Antibody_031816
Human peripheral blood monocytes were stained with purified CD92 (clone VIM15b, filled histogram) or mouse IgG2b, κ isotype control (open histogram), followed by anti-mouse IgG PE.
  • VIM15b_PURE_CD92_Antibody_031816
    Human peripheral blood monocytes were stained with purified CD92 (clone VIM15b, filled histogram) or mouse IgG2b, κ isotype control (open histogram), followed by anti-mouse IgG PE.
Cat # Size Price Save
371402 100 µg ¥45,320
Description

CD92, also known as CDW92 and CTL1, is a 70kD choline transporter-like transmembrane protein. CD92 is important for transport of choline across the membrane for synthesis of cell membrane components and the neurotransmitter, acetylcholine. CD92 is primarily expressed on monocytes and neutrophils, but can also be found on other myeloid and T-cell subsets. Ionomycin or calcium ionophore mediates the maturation of monocytic dendritic cells causing down-regulation of CD92 but treatment with IL-10 causes re-expression.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
MV4-11
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Wille S, et al. 2001. J. Immunol. 167:5795.
RRID
AB_2572178 (BioLegend Cat. No. 371402)

Antigen Details

Structure
70kD choline transporter-like transmembrane protein.
Distribution

Monocytes, neutrophils, and certain groups of T-cells.

Function
Transport of choline through the cell membrane.
Interaction
Choline.
Cell Type
Monocytes, Neutrophils, T cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Schenkel LC, et al. 2015. FASEB J. 29:1663.
2. Yamada T, et al. 2011. Neurochem. Int. 58:354.
3. Fullerton MD, et al. 2006. Am. J. Physiol. Cell Physiol. 290:C1230.

Gene ID
23466 View all products for this Gene ID
UniProt
View information about CD92 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 03/22/2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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