United States ($) USD
Austria (€) EUR
Belgium (€) EUR
Finland (€) EUR
France (€) EUR
Germany (€) EUR
Ireland (€) EUR
Japan (¥) JPY
Luxembourg (€) EUR
Netherlands (€) EUR
Switzerland (CHF) CHF
United Kingdom (£) GBP
- Clone
- QA21A15 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Ig delta chain C region
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with anti-human CD19 FITC and purified anti-human IgD recombinant (clone QA21A25) (left) or purified mouse IgG1, κ isotype control (right), followed by PE goat anti-mouse IgG.
IgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It has 3 Ig-like domains and exists in a transmembrane and a soluble form. In general, IgD is not secreted and its expression is usually lost after the Ig isotype switch. After antigen binding, IgD signals through the CD79a/CD79b (Igα/Igβ) heterodimer, resulting in the activation of the B cell.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2927963 (BioLegend Cat. No. 385502)
Antigen Details
- Structure
- Ig family
- Distribution
-
Naïve B cells
- Function
- Antigen binding, B cell activation
- Interaction
- The CD79a/CD79b heterodimer
- Cell Type
- B cells
- Biology Area
- Adaptive Immunity, Immunology
- Antigen References
-
- Geisberger R, et al. 2006. Immunology. 118:429-37
- Weller S, et al. 2005. Eur. J. Immunol. 35:2789-92
- Brandtzaeg P and Johansen FE. 2005. Immunol. Rev. 206:32-63
- Gene ID
- 3495 View all products for this Gene ID
- UniProt
- View information about IgD on UniProt.org
Other Formats
View All IgD Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human IgD Recombinant Antibody | QA21A15 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human IgD Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu...
Follow Us