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Purified anti-human MUC-13 Antibody

Pricing & Availability
Clone
TCC16 (See other available formats)
Regulatory Status
RUO
Other Names
DRCC1, RECC, Mucin-13
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
TCC16_Purified_MUC-13_Antibody_FC_100314
Human colon cancer cell line, HT-29, was stained with purified MUC-13 (clone TCC16, filled histogram) or purified mouse IgG1, κ isotype control (open histogram) followed by anti-mouse IgG PE.
  • TCC16_Purified_MUC-13_Antibody_FC_100314
    Human colon cancer cell line, HT-29, was stained with purified MUC-13 (clone TCC16, filled histogram) or purified mouse IgG1, κ isotype control (open histogram) followed by anti-mouse IgG PE.
Cat # Size Price Save
363902 100 µg ¥58,300
Description

MUC-13 is an epithelial and hematopoietic transmembrane mucin that is highly expressed in epithelial tissues, especially in the GI and respiratory tracts. It has moderate to high levels of expression in the kidneys, small intestine, appendix, and stomach. MUC-13 mediates various signaling pathways and may be a potential target for antibody-mediated cancer treatment.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human pancreatic cell line, TCC-PAN2
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Wiedenmann S, et al. 2021. Nat Biomed Eng. 5:897. PubMed
RRID
AB_2564377 (BioLegend Cat. No. 363902)

Antigen Details

Structure
54 kD transmembrane glycoprotein; α (extracellular tail) and β (cytoplasmic tail) subunits.
Distribution
Highly expressed in epithelial tissues.
Cell Type
Epithelial cells
Biology Area
Cell Biology, Immunology, Signal Transduction
Antigen References

1. Gupta BK, et al. 2012. J. Histochem. Cytochem. 60:822.
2. Chauhan SC, et al. 2012. Mol. Cancer Ther. 11:24.
3. Maher DM, et al. 2011. Mol. Cancer Res. 9:531.
4. Chauhan SC, et al. 2009. Cancer Res. 69:765.
5. Shimamura T, et al. 2005. Cancer Sci. 96:265.

Gene ID
56667 View all products for this Gene ID
UniProt
View information about MUC-13 on UniProt.org
Go To Top Version: 1    Revision Date: 10/09/2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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