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- Clone
- TCC16 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- DRCC1, RECC, Mucin-13
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human colon cancer cell line, HT-29, was stained with purified MUC-13 (clone TCC16, filled histogram) or purified mouse IgG1, κ isotype control (open histogram) followed by anti-mouse IgG PE.
MUC-13 is an epithelial and hematopoietic transmembrane mucin that is highly expressed in epithelial tissues, especially in the GI and respiratory tracts. It has moderate to high levels of expression in the kidneys, small intestine, appendix, and stomach. MUC-13 mediates various signaling pathways and may be a potential target for antibody-mediated cancer treatment.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human pancreatic cell line, TCC-PAN2
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
-
AB_2564377 (BioLegend Cat. No. 363902)
Antigen Details
- Structure
- 54 kD transmembrane glycoprotein; α (extracellular tail) and β (cytoplasmic tail) subunits.
- Distribution
- Highly expressed in epithelial tissues.
- Cell Type
- Epithelial cells
- Biology Area
- Cell Biology, Immunology, Signal Transduction
- Antigen References
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1. Gupta BK, et al. 2012. J. Histochem. Cytochem. 60:822.
2. Chauhan SC, et al. 2012. Mol. Cancer Ther. 11:24.
3. Maher DM, et al. 2011. Mol. Cancer Res. 9:531.
4. Chauhan SC, et al. 2009. Cancer Res. 69:765.
5. Shimamura T, et al. 2005. Cancer Sci. 96:265. - Gene ID
- 56667 View all products for this Gene ID
- UniProt
- View information about MUC-13 on UniProt.org
Related FAQs
Other Formats
View All MUC-13 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human MUC-13 | TCC16 | FC |
| PE anti-human MUC-13 | TCC16 | FC |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human MUC-13
Human colon cancer cell line, HT-29, was stained with purifi... -
PE anti-human MUC-13
HT29 cells were stained with MUC-13 (Clone TCC16) PE (closed...
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