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- Clone
- BM-1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- myeloid specific antigen, p183 DNA-binding cytoplasmic protein
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Human myeloid cell line HL60 intracellular stained with purified BM-1, followed by anti-mouse IgG FITC
BM-1 antigen is a 183 kD myeloid-specific-DNA-binding protein which is expressed in myeloid cells, including myeloid precursors and mature granulocytes. It is also expressed in chronic myeloid leukemia (CML) and M2 and M3 acute myeloid leukemias (AML) as well as myelomonocytic leukemias, but not in T, B, NK and other non-hematopoietic cells. The biological function of this antigen is not clear, although it has been proposed that BM-1 may play a role in the differentiation of myeloid cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- PWM-stimulated human PBL
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICFC - Quality tested
IHC-P, IHC-F, IP - Reported in the literature, not verified in house - Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
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Additional reported (for the relevant formats) applications include: immunohistochemical staining of frozen and paraffin sections1, and immunoprecipitation1.
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Application References
(PubMed link indicates BioLegend citation) -
- Epstein AL, et al.1987. Blood 70:1124.
- RRID
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AB_893592 (BioLegend Cat. No. 327102)
Antigen Details
- Structure
- 183 kD, DNA-binding protein
- Distribution
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In myeloid cells
- Antigen References
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1. Epstein AL, et al. 1987. Blood 70:1124.
- Gene ID
- 861 View all products for this Gene ID
- UniProt
- View information about myeloid antigen on UniProt.org
Related FAQs
Other Formats
View All myeloid antigen Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human myeloid antigen | BM-1 | ICFC,IHC-P,IHC-F,IP |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human myeloid antigen
Human myeloid cell line HL60 intracellular stained with puri...
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