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Purified anti-human TCR α/β Recombinant Antibody

Pricing & Availability
Clone
QA20B12 (See other available formats)
Regulatory Status
RUO
Other Names
α/β TCR, TCR α/β
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA20B12_PURE_TCR_Antibody_1_042622
Human peripheral blood lymphocytes were stained with anti-human CD3 FITC and purified anti-human TCR α/β recombinant (clone QA20B12) (left) or purified mouse IgG1, κ isotype control (right) followed by PE goat anti-mouse IgG.
  • QA20B12_PURE_TCR_Antibody_1_042622
    Human peripheral blood lymphocytes were stained with anti-human CD3 FITC and purified anti-human TCR α/β recombinant (clone QA20B12) (left) or purified mouse IgG1, κ isotype control (right) followed by PE goat anti-mouse IgG.
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Cat # Size Price Save
380802 100 µg ¥27,280
Description

The α/β T-cell receptor (TCR) recognizes a peptide bound to MHC leading to T cell activation. α/β TCR expressing T cells comprise more than 90% of CD3+ T cells in peripheral blood. The clone QA20B12 antibody only reacts with the α/β TCR, not the γ/δ TCR.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone QA20B12 can completely block the binding of clone IP26 on target cells.

RRID
AB_2924573 (BioLegend Cat. No. 380802)

Antigen Details

Structure
Ig superfamily
Distribution

T cells, thymocytes

Function
Antigen recognition, T cell activation
Interaction
CD3
Ligand/Receptor
Peptide bound to MHC
Cell Type
T cells, Thymocytes, Tregs
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References
  1. Marchalonis JJ, et al. 2002. J Mol Recognit. 15:260-71.
Gene ID
6955 View all products for this Gene ID 6957 View all products for this Gene ID
UniProt
View information about TCR alpha/beta on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 03/17/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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