- Clone
- S17007L (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Siglec-5
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
CD170, also known as Siglec-F, Siglec-5, is a member of the Sialic acid-binding Ig-like lectin family, type I single pass transmembrane protein, with 4 extracellular Ig-like domains and 2 ITIM motifs in the cytoplasmic domain; preferentially binds [alpha]-2,3-linked sialic acid. Siglec F is expressed in eosinophils, alveolar macrophages and intestinal microfold (M) cells and induces apoptosis of the lung eosinophis during allergic asthma.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
-
AB_2810420 (BioLegend Cat. No. 155502)
Antigen Details
- Structure
- Member of the Sialic acid-binding Ig-like lectin family, type I, single pass, transmembrane protein, 4 extracellular Ig-like domains, 2 ITIM motifs in the cytoplasmic domain
- Distribution
-
Eosinophils, alveolar macrophages, intestinal microfold (M) cells
- Function
- Induces apoptosis in eosinophils
- Ligand/Receptor
- [alpha]-2,3-linked sialic acid
- Cell Type
- Eosinophils, Macrophages
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Siglec Molecules
- Antigen References
-
- Gicheva N, et al. 2016. Biochem. Biophys. Res. Commun. 479:1.
- Kiwamoto T, et al. 2015. J. Allergy Clin. Immunol. 135:1329.
- Suzukawa M, et al. 2013. J. Immunol. 190:5939.
- Patnode ML, et al. 2013. J. Biol. Chem. 288:26533.
- Gene ID
- 233186 View all products for this Gene ID
- UniProt
- View information about CD170 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD170 (Siglec-F)... -
FITC anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
PE anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
APC anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
Brilliant Violet 421™ anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
Biotin anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with CD193 (CCR3, clo... -
TotalSeq™-A0431 anti-mouse CD170 (Siglec-F)
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TotalSeq™-C0431 anti-mouse CD170 (Siglec-F)
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TotalSeq™-B0431 anti-mouse CD170 (Siglec-F)
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Alexa Fluor® 647 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
KIRAVIA Blue 520™ anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
Alexa Fluor® 488 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PerCP/Cyanine5.5 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PE/Cyanine7 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PE/Dazzle™ 594 anti-mouse CD170 (Siglec-F) Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
APC/Cyanine7 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
Alexa Fluor® 700 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
PerCP/Fire™ 806 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
Brilliant Violet 711™ anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
APC/Fire™ 750 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD19... -
APC/Fire™ 810 anti-mouse CD170 (Siglec-F)
C57BL/6 mouse splenocytes were stained with anti-mouse CD193... -
Spark Blue™ 574 anti-mouse CD170 (Siglec-F) (Flexi-Fluor™)
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Spark Blue™ 550 anti-mouse CD170 (Siglec-F) (Flexi-Fluor™)
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