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- Clone
- F11-172 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Mb-1, Igα
- Isotype
- Armenian Hamster IgG
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Mouse CD79a (Ig α chain) is a 47 kD type I integral membrane protein, known as mb-1 or Ig α. It forms a heterodimer with CD79b (Ig β chain). The CD79a and CD79b heterodimers are associated with surface IgM to form the B-cell receptor (BCR) that is necessary for signal transduction via the BCR in mature B cells. CD79a may play a role in mediating the transport of IgM to the cell surface. Clone F11-172 antibody recognizes the 47 kD membrane glycoprotein present on B lymphocytes.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICFC - Quality tested
IP - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Kraus M, et al. 2001. J. Exp. Med. 194:455
- Product Citations
-
- RRID
-
AB_1595656 (BioLegend Cat. No. 133102)
Antigen Details
- Structure
- A 47 kD membrane glycoprotein which associates with CD79b to form part of B-cell receptor complex.
- Distribution
- CD79a is expressed on B cells at various differentiation stages, from pre-B cell to plasma cells. It is expressed probably before expression of cytoplasmic µu chain.
- Function
- Mediating the transport of IgM to the cell surface.
- Ligand/Receptor
- CD79a/CD79b heterodimers are associated with surface IgM to form B cell receptor complex (BCR) to recognize specific antigen.
- Cell Type
- B cells, Plasma cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Schamel W, et al. 2000. Immunity 13:5
2. Taddie JA, et al. 1994. J. Biol. Chem. 269:13529 - Gene ID
- 12518 View all products for this Gene ID
- UniProt
- View information about CD79a on UniProt.org
Other Formats
View All CD79a Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse CD79a (Igα) | F11-172 | ICFC,IP |
| PE anti-mouse CD79a (Igα) | F11-172 | ICFC |
| APC anti-mouse CD79a (Igα) | F11-172 | ICFC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD79a (Igα)
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PE anti-mouse CD79a (Igα)
C57BL/6 mouse splenocytes were intracellularly stained with ... -
APC anti-mouse CD79a (Igα)
C57BL/6 splenocytes were surface stained with CD45R/B220 (cl...
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