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- Clone
- MM3 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- FcμR, FcmR, Fc mu receptor, IgM Fc receptor, FAIM3, TOSO
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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C57BL/6 mouse splenocytes were stained with CD19 APC and FcμR (FAIM3) (clone MM3) purified (left) or mouse IgG1, κ purified isotype control (right) followed by PE anti-mouse IgG1.
The mouse FCMR (also known as FcµR, FAIM3, TOSO) is a type 1 transmembrane glycoprotein that belonging to the immunoglobulin (Ig) gene superfamily. FcμR had a molecular weight of ~60-kD. In mouse, FCMR is expressed only on B lymphocytes and not on T cells, NK cells, dendritic cells, or myeloid cells. FCMR is involved in the regulation of humoral immunity including IgM homeostasis and B cell survival.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BW5147 expressing mouse FCµR
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Honjo K, et al. 2012. Proc. Natl. Acad. Sci. U S A. 109:15882-7.
- Shima H, et al. 2010. Int. Immunol. 22:149-156.
- Product Citations
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- RRID
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AB_2814094 (BioLegend Cat. No. 157802)
Antigen Details
- Structure
- ~60 kD transmembrane sialoglycoprotein extracellular Ig-like domain
- Distribution
-
B lymphocytes
- Function
- Regulation of humeral immunity including IgM homeostasis and B cell survival.
- Ligand/Receptor
- IgM Fc
- Cell Type
- B cells
- Biology Area
- Adaptive Immunity, Immunology, Signal Transduction
- Molecular Family
- Fc Receptors
- Antigen References
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- Honjo K, et al. 2013. Proc. Natl. Acad. Sci. U S A. 110:2540-41.
- Liu J, et al. 2018. Front. Immunol. 9:160.
- Gene ID
- 69169 View all products for this Gene ID
- UniProt
- View information about Fc muR on UniProt.org
Other Formats
View All FcμR Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse FcμR (FAIM3) | MM3 | FC |
| Biotin anti-mouse FcμR (FAIM3) | MM3 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse FcμR (FAIM3)
C57BL/6 mouse splenocytes were stained with CD19 APC and Fcμ... -
Biotin anti-mouse FcμR (FAIM3)
C57BL/6 mouse splenocytes were surface stained with anti-mou...
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