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Purified anti-mouse FcμR (FAIM3) Antibody

Pricing & Availability
Clone
MM3 (See other available formats)
Regulatory Status
RUO
Other Names
FcμR, FcmR, Fc mu receptor, IgM Fc receptor, FAIM3, TOSO
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
MM3_PURE_FcmuR_Antibody_080219
C57BL/6 mouse splenocytes were stained with CD19 APC and FcμR (FAIM3) (clone MM3) purified (left) or mouse IgG1, κ purified isotype control (right) followed by PE anti-mouse IgG1.
  • MM3_PURE_FcmuR_Antibody_080219
    C57BL/6 mouse splenocytes were stained with CD19 APC and FcμR (FAIM3) (clone MM3) purified (left) or mouse IgG1, κ purified isotype control (right) followed by PE anti-mouse IgG1.
Cat # Size Price Save
157802 500 µg ¥127,820
Description

The mouse FCMR (also known as FcµR, FAIM3, TOSO) is a type 1 transmembrane glycoprotein that belonging to the immunoglobulin (Ig) gene superfamily. FcμR had a molecular weight of ~60-kD. In mouse, FCMR is expressed only on B lymphocytes and not on T cells, NK cells, dendritic cells, or myeloid cells. FCMR is involved in the regulation of humoral immunity including IgM homeostasis and B cell survival.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
BW5147 expressing mouse FCµR
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Honjo K, et al. 2012. Proc. Natl. Acad. Sci. U S A. 109:15882-7. 
  2. Shima H, et al. 2010. Int. Immunol. 22:149-156. 
Product Citations
  1. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
RRID
AB_2814094 (BioLegend Cat. No. 157802)

Antigen Details

Structure
~60 kD transmembrane sialoglycoprotein extracellular Ig-like domain
Distribution

B lymphocytes

Function
Regulation of humeral immunity including IgM homeostasis and B cell survival.
Ligand/Receptor
IgM Fc
Cell Type
B cells
Biology Area
Adaptive Immunity, Immunology, Signal Transduction
Molecular Family
Fc Receptors
Antigen References
  1. Honjo K, et al. 2013. Proc. Natl. Acad. Sci. U S A. 110:2540-41. 
  2. Liu J, et al. 2018. Front. Immunol. 9:160. 
Gene ID
69169 View all products for this Gene ID
UniProt
View information about Fc muR on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 08/02/2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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