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- Clone
- W16163A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Leukemia inhibitory factor receptor alpha, Leukemia inhibitory factor receptor, Lifr, LIFR-a
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
C57BL/6 mouse bone marrow cells were stained with IFNAR-1 APC and purified LIFR (clone W16163A) (left) or purified rat IgG2b, κ isotype control (right), followed by goat anti-rat IgG PE. Dot plots are gated on lymphoid cells. -
C57BL/6 mouse splenocytes were stained with IFNAR-1 APC and purified LIFR (clone W16163A) (left) or purified rat IgG2b, κ isotype control (right), followed by goat anti-rat IgG PE.
Leukemia inhibitory factor (LIFR) receptor alpha belongs to the type I cytokine receptor family, combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of LIF, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in theadult and the embryo.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse LIFR
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
W16163A can be used for surface staining of LIFR expressed on mouse splenocytes and bone marrow cells (tested on C57BL/6).
- RRID
-
AB_2876550 (BioLegend Cat. No. 158902)
Antigen Details
- Distribution
-
IFNAR+ pDCs, IFNAR+ lymphocytes, and Ly6C+ lymphocytes. Dim expression by CD11b+ and CD90.2+ lymphocytes.
- Ligand/Receptor
- LIFR combines with gp130 to form a receptor complex that mediates the action of LIF
- Cell Type
- Macrophages, Monocytes
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
- Wang T, et al. 2019. Mol Med Rep. 19:4719-26.
- Cheng L, et al. 1994. Development. 120:3145-3513.
- Mikelonis D, et al. 2014. Orphanet Journal of Rare Diseases. 9:34.
- Gene ID
- 16880 View all products for this Gene ID
- UniProt
- View information about LIFR on UniProt.org
Related FAQs
Other Formats
View All LIFR Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse LIFR | W16163A | FC |
| PE/Cyanine7 anti-mouse LIFR | W16163A | FC |
| APC anti-mouse LIFR | W16163A | FC |
| PE anti-mouse LIFR | W16163A | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse LIFR
C57BL/6 mouse bone marrow cells were stained with IFNAR-1 AP... 
C57BL/6 mouse splenocytes were stained with IFNAR-1 APC and ... -
PE/Cyanine7 anti-mouse LIFR
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
APC anti-mouse LIFR
C57 mouse bone marrow was stained with anti-mouse Ly-6C FITC... -
PE anti-mouse LIFR
C57BL/6 mouse bone marrow cells were stained with anti-mouse...
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