- Clone
- N196/16 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Zinc finger protein 746, parkin-interacting sustrate, parkin-interacting substrate, ZNF746
- Previously
-
Covance Catalog# MMS-5178
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Parkin-interacting substrate (PARIS), also known as zing finger protein 746 (ZNF746), accumulates in human Parkinson's disease brain. PARIS levels are controlled by parkin, and dysregulation of parkin leads to PARIS-dependent loss of dopaminergic neurons.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a fusion protein corresponding to amino acids 1-322 (N-terminus) of human PARIS/ZNF746.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
IHC-P - Quality tested
WB - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 µg/ml is suggested. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 µg/ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
This antibody is effective in immunoblotting (WB) and immunohistochemistry (IHC-P).
- RRID
-
AB_2564842 (BioLegend Cat. No. 820601)
Antigen Details
- Structure
- Expected MW: 60 kD
- Biology Area
- Cell Biology, Mitochondrial Function, Neuroinflammation, Neuroscience
- Molecular Family
- Enzymes and Regulators
- Gene ID
- 155061 View all products for this Gene ID
- UniProt
- View information about PARIS on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All PARIS (ZNF746) Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-PARIS (ZNF746) | N196/16 | IHC-P,WB |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
Follow Us