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Purified anti-pig CD8 Antibody

Pricing & Availability
Clone
76-2-11 (See other available formats)
Regulatory Status
RUO
Other Names
CD8a, Leu2 T-lymphocyte antigen, LEU2, MAL, T8, CD8α
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
76-2-11_PURE_CD8alpha_Antibody_082522
Porcine peripheral blood lymphocytes were stained with anti-pig CD3ε APC and purified anti-pig CD8α (clone 76-2-11) (left) or purified mouse IgG2a, κ isotype control (right), followed by PE anti-mouse IgG.
  • 76-2-11_PURE_CD8alpha_Antibody_082522
    Porcine peripheral blood lymphocytes were stained with anti-pig CD3ε APC and purified anti-pig CD8α (clone 76-2-11) (left) or purified mouse IgG2a, κ isotype control (right), followed by PE anti-mouse IgG.
Cat # Size Price Save
251202 100 µg ¥35,200
Description

CD8 is a 35 kD type I transmembrane glycoprotein and is expressed as either a CD8αα homodimer or a CD8αβ heterodimer. It functions as a MHC Class I co-receptor for antigen recognition. It is highly expressed in thymocytes, cytotoxic T-cells, and NK cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Pig
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2924499 (BioLegend Cat. No. 251202)

Antigen Details

Structure
Type I transmembrane glycoprotein, expressed as CD8αα homodimer or a CD8αβ heterodimer
Distribution

Thymocytes, suppressor/cytotoxic subpopulation of peripheral T cells

Function
Co-receptor, stabilizes MHC Class I-TCR interaction
Ligand/Receptor
T-cell receptors, MHC-I
Cell Type
NK cells, T cells, Thymocytes
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References
  1. Wang W, et al. 2015. Mol Genet Genomics. 290:1447-56.
Gene ID
396627 View all products for this Gene ID
UniProt
View information about CD8 on UniProt.org
Go To Top Version: 1    Revision Date: 07/25/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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