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- Clone
- OX-19 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Ly-1, Tp67, Leu-1, T1, Lyt-1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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LOU rat splenocytes stained with OX-19 purified, followed by anti-mouse IgG PE
CD5 is a 67 kD glycoprotein, also known as Lyt-1, Ly-1 or Ly-12. It is a member of the scavenger receptor superfamily and primarily expressed on thymocytes and mature peripheral T lymphocytes, but not on NK cells, intestinal intraepithelial gamma/delta T cells. A CD5+ B cell subset (B-1) has not been characterized in that rat.
Product DetailsProduct Details
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Rat thymocyte lentil lectin-binding glycoproteins
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
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FC - Quality tested
ICC - Reported in the literature, not verified in house - Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Dallman MJ, et al. 1984. Eur. J. Immunol. 14:260.
- Vemeer LA, et al. 1994. Eur. J. Immunol. 24:585.
- RRID
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AB_1089042 (BioLegend Cat. No. 203501)
Antigen Details
- Structure
- CD5 is a 67 kD glycoprotein of scavenger receptor superfamily. It is expressed on thymocytes, T cells and small subset of B cells.
- Distribution
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Expressed on thymocytes, peripheral T cells, and some thymic dendritic cells. It should be noted that a CD5+ subset of B cells has not been characterized in the rat by OX-19. Most gamma/delta T cells do not express CD5.
- Function
- Important in T-B cell interaction.
- Ligand/Receptor
- CD72
- Biology Area
- Immunology, Costimulatory Molecules
- Molecular Family
- CD Molecules, TCRs
- Antigen References
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1. Vermeer LA, et al. 1994. Eur. J. Immunol. 24:585.
- Gene ID
- 54236 View all products for this Gene ID
- UniProt
- View information about CD5 on UniProt.org
Related FAQs
Other Formats
View All CD5 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-rat CD5 | OX-19 | FC,ICC |
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Purified anti-rat CD5
LOU rat splenocytes stained with OX-19 purified, followed by...
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