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- Clone
- 6G2/CD98 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- 4F2, Ly10
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Rat splenocytes were stained with purified anti-rat CD98 (clone 6G2/CD98) (filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by goat anti-mouse IgG PE. -
Frozen rat spleen section was fixed with 4% paraformaldehyde (PFA) for 10 minutes, and blocked with 5% FBS for 30 minutes at room temperature. Then the section was stained with 10 µg/ml of purified anti-rat CD98 (clone 6G2/CD98) overnight at 4°C, followed by 2.5 µg/mL of Alexa Fluor® 647 anti-mouse IgG (clone Poly4053) (red) for two hours at room temperature. Nuclei were counterstained with DAPI (blue). The image was captured by 10X objective.
CD98 is a cell surface glycoprotein of 125 KDa consisting of an 85 KDa heavy chain and a 40 KDa light chain.It is expressed on T, B, NK cells, granulocytes and many cell lines and tumor cells.CD98 has been shown to be involved in sodium-dependent calcium flux in muscles cells and lymphocyte activation.
Product DetailsProduct Details
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. For immunohistochemistry, a concentration range of 5.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2876579 (BioLegend Cat. No. 206402)
Antigen Details
- Structure
- Disulfide-linked heterodimer, 80 kD and 45 kD reduced, 125 kD unreduced
- Distribution
-
Broadly expressed on activated and transformed cells, not hematopoietic cell-specific. Lower levels on resting cells
- Function
- Potential amino acid transporter (neutral and dibasic amino acids) also involved in the activation of lymphocytes and integrin signaling. May be a target antigen for NK cells
- Cell Type
- B cells, Granulocytes, Leukocytes, Lymphocytes, NK cells, T cells
- Biology Area
- Cell Adhesion, Cell Proliferation and Viability
- Molecular Family
- CD Molecules
- Gene ID
- 50567 View all products for this Gene ID
- UniProt
- View information about CD98 on UniProt.org
Related FAQs
Other Formats
View All CD98 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-rat CD98 | 6G2/CD98 | FC,IHC-F |
| APC anti-rat CD98 Antibody | 6G2/CD98 | FC |
| PE anti-rat CD98 Antibody | 6G2/CD98 | FC |
| FITC anti-rat CD98 | 6G2/CD98 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-rat CD98
Rat splenocytes were stained with purified anti-rat CD98 (cl... 
Frozen rat spleen section was fixed with 4% paraformaldehyde... -
APC anti-rat CD98 Antibody
Rat splenocytes were stained with anti-rat CD98 APC (clone 6... -
PE anti-rat CD98 Antibody
Rat splenocytes were stained with anti-rat CD98 PE (clone 6G... -
FITC anti-rat CD98
Rat splenocytes were stained with anti-rat CD98 FITC (clone ...
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