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PE anti-human CD96 (TACTILE) Antibody

Pricing & Availability
Clone
NK92.39 (See other available formats)
Regulatory Status
RUO
Other Names
Tactile (T cell-activated increased late expression)
Isotype
Mouse IgG1, κ
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Product Citations
publications
NK92dot39_PE_011409.jpg
Human peripheral blood lymphocytes stained with CD19 (HIB19) APC and NK92.39 PE
  • NK92dot39_PE_011409.jpg
    Human peripheral blood lymphocytes stained with CD19 (HIB19) APC and NK92.39 PE
Compare all formats See PE spectral data
Cat # Size Price Save
338405 25 tests ¥32,120
338406 100 tests ¥75,020
Description

CD96, known as TACTILE (T cell-activated increased late expression), is a 160 kD type I transmembrane glycoprotein and is a member of the Ig superfamily molecules. It is expressed on NK cells, T cells (up-regulated upon activation), and some acute myeloid leukemia (AML) cells, but not on normal B and myeloid cells. A soluble form of CD96 has been found in serum. CD96 is involved in T- and NK-cell adhesion through interaction with its ligand, CD155 (polio virus receptor).

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications include: block interaction of CD96 with PVR and functional assay

Application References

(PubMed link indicates BioLegend citation)
  1. Fuchs A, et al. 2004. J. Immunol. 172:3994
  2. Manes TD, et al. 2011. J. Immunol. 186:1763. PubMed
Product Citations
  1. Wang CQ, et al. 2023. Cells. 12: . PubMed
  2. Ho CH, et al. 2021. Arthritis Res Ther. 23:199. PubMed
  3. Zhang X, et al. 2021. Front Immunol. 12:602492. PubMed
  4. Pahl JHW, et al. 2018. Cancer Immunol Res. 0.609027778. PubMed
RRID
AB_2291404 (BioLegend Cat. No. 338405)
AB_2291404 (BioLegend Cat. No. 338406)

Antigen Details

Structure
160 kD, type I transmembrane protein, Ig superfamily
Distribution

NK cells, T cells (upregulated upon activation)

Ligand/Receptor
CD155 (PVR)
Cell Type
NK cells, T cells
Biology Area
Immunology, Innate Immunity, Inhibitory Molecules
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Hosen N, et al. 2007. Proc. Natl. Acad. Sci. USA 104:11008
3. Gong J, et al. 2008. Clin. Exp. Immunol.

Gene ID
10225 View all products for this Gene ID
UniProt
View information about CD96 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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