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FITC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-f11
C57BL/6 splenocytes stained with 30-F11 FITC
  • 30-f11
    C57BL/6 splenocytes stained with 30-F11 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103107 50 µg 29€
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103108 500 µg 84€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  2. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  3. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  4. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  5. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  6. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  7. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  8. Sefik E, et al. 2022. Nature. 606:585. PubMed
  9. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  10. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  11. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  12. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  13. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  14. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  15. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  16. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  17. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  18. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  19. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  20. Zheng Z, et al. 2022. Cells. 11: . PubMed
  21. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  22. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  23. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  24. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  25. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  26. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  27. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  28. Liu X, et al. 2022. Pain. 163:508. PubMed
  29. González H, et al. 2022. Cell. 185:729. PubMed
  30. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  31. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  32. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  33. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  34. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  35. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  36. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  37. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  38. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  39. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  40. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  41. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  42. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  43. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  44. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  45. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  46. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  47. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  48. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  49. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  50. Li L, et al. 2023. iScience. 26:106095. PubMed
  51. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  52. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  53. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  54. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  55. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  56. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  57. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  58. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  59. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  60. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  61. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  62. Wang X, et al. 2023. Nature. 618:808. PubMed
  63. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  64. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  65. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  66. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  67. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  68. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  69. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  70. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  71. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  72. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  73. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  74. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  75. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  76. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  77. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  78. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  79. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  80. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  81. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  82. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  83. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  84. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  85. Zhu H, et al. 2018. Elife. 7:. PubMed
  86. Liu X, et al. 2020. Nature. . PubMed
  87. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  88. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  89. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  90. Saito S, et al. 2020. Nutrients. 12:. PubMed
  91. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  92. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  93. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  94. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  95. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  96. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  97. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  98. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  99. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  100. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  101. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  102. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  103. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  104. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  105. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  106. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  107. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  108. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  109. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  110. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  111. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  112. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  113. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  114. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  115. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  116. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  117. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  118. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  119. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  120. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  121. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  122. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  123. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  124. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  125. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  126. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  127. Zhang X, et al. 2022. Cells. 11:. PubMed
  128. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  129. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  130. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  131. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  132. Plein A, et al. 2018. Nature. 562:223. PubMed
  133. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  134. Green DP, et al. 2019. Neuron. 101:412. PubMed
  135. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  136. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  137. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  138. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  139. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  140. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  141. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  142. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  143. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  144. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  145. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  146. Li J, et al. 2020. Elife. 9:00. PubMed
  147. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  148. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  149. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  150. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  151. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  152. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  153. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  154. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  155. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  156. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  157. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  158. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  159. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  160. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  161. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  162. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  163. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  164. Wan X, et al. 2018. Nature. 560:107. PubMed
  165. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  166. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  167. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  168. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  169. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  170. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  171. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  172. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  173. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  174. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  175. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  176. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  177. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  178. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  179. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  180. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  181. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  182. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  183. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  184. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  185. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  186. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  187. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  188. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  189. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  190. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  191. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  192. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  193. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  194. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  195. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  196. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  197. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  198. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  199. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  200. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  201. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  202. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  203. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  204. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  205. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  206. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  207. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  208. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  209. Long JT, et al. 2022. Elife. 11:. PubMed
  210. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  211. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  212. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  213. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  214. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  215. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  216. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  217. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  218. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  219. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  220. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  221. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  222. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  223. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  224. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  225. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  226. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  227. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  228. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  229. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  230. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  231. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  232. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  233. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  234. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  235. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  236. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  237. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  238. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  239. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  240. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  241. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  242. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  243. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  244. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  245. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  246. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  247. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  248. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  249. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  250. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  251. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  252. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  253. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  254. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  255. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  256. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  257. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  258. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  259. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  260. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  261. Sheng J, et al. 2021. eLife. 10:00. PubMed
  262. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  263. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  264. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  265. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  266. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  267. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  268. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  269. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  270. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  271. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  272. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  273. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  274. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  275. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  276. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  277. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  278. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  279. Dingler FA, et al. 2020. Mol Cell. . PubMed
  280. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  281. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  282. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
  283. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  284. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  285. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  286. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  287. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  288. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  289. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  290. Wolf Y, et al. 2019. Cell. 179:219. PubMed
RRID
AB_312972 (BioLegend Cat. No. 103107)
AB_312972 (BioLegend Cat. No. 103108)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD45
Specificity Alt (DOES NOT SHOW ON TDS):
CD45
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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