- Clone
- QA18A21 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Leu-19, NKH1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
398805 | 25 tests | 110€ | ||||
398806 | 100 tests | 237€ |
CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- RRID
-
AB_2894509 (BioLegend Cat. No. 398805)
AB_2894509 (BioLegend Cat. No. 398806)
Antigen Details
- Structure
- Ig superfamily, single transmembrane or GPI-anchored glycoprotein
- Distribution
-
NK cells, T subset, neural tissue, some LGL and myeloid leukemias
- Function
- Adhesion
- Ligand/Receptor
- Heparin sulfate
- Cell Type
- B cells, Leukemia, Mesenchymal Stem Cells, Neurons, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Stem Cells, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Rosental B, et al. 2011. J Immunol. 187:5693. PubMed
- Correia DV, et al. 2011. Blood. 118:992. PubMed
- Schlecker E, et al. 2014. Cancer Res. 74:3429. PubMed
- Snyder JM, et al. 2014. PLoS One. 9:e107257. PubMed
- Siebert N, et al. 2014. PLoS One. 9:e107692. PubMed
- Rider P, et al. 2015. J Immunol. 195:1705-12. PubMed
- Davis ZB, et al. 2011. J Vis Exp. 49: 2668. PubMed
- Robin JD, et al. 2015. J Vis Exp. 95: 52307. PubMed
- Ames E, et al. 2015. J Immunol. 195: 4010-9. PubMed
- Laroni A, et al. 2016. J Autoimmun. 72:8-18. PubMed
- Pachnio A, et al. 2016. PLoS Pathog. 12:e1005832. PubMed
- Wouters K, et al. 2017. Sci Rep. 7:42665. PubMed
- Gene ID
- 4684 View all products for this Gene ID
- UniProt
- View information about CD56 on UniProt.org
Related FAQs
Other Formats
View All CD56 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD56 (NCAM) Recombinant Antibody | QA18A21 | FC |
Purified anti-human CD56 (NCAM) Recombinant Antibody | QA18A21 | FC |
APC anti-human CD56 (NCAM) Recombinant Antibody | QA18A21 | FC |
PE/Dazzle™ 594 anti-human CD56 (NCAM) Recombinant Antibody | QA18A21 | FC |
PerCP/Cyanine5.5 anti-human CD56 (NCAM) Recombinant Antibody | QA18A21 | FC |
PE/Cyanine7 anti-human CD56 (NCAM) Recombinant Antibody | QA18A21 | FC |
APC/Cyanine7 anti-human CD56 (NCAM) Recombinant Antibody | QA18A21 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
PE anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes stained with CD3 APC and ... Human peripheral blood lymphocytes stained with CD16 FITC an... -
Purified anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes stained with purified rec... Human peripheral blood lymphocytes stained with purified rec... -
APC anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Dazzle™ 594 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Cyanine5.5 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Cyanine7 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
APC/Cyanine7 anti-human CD56 (NCAM) Recombinant Antibody
Human peripheral blood lymphocytes stained with anti-human C...
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