- Clone
- B6 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- T cell receptor V δ 2, TRDV2, TCRDV102S1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
331411 | 25 tests | 181€ | ||||
331412 | 100 tests | 357€ |
The Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 711™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Brilliant Violet 711™ excites at 405 nm and emits at 711 nm. The bandpass filter 710/50 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 711™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- Application References
-
- Rojas RE, et al. 2005. J. Infect. Dis. 192:1806.
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
- Product Citations
-
- RRID
-
AB_2565421 (BioLegend Cat. No. 331411)
AB_2565421 (BioLegend Cat. No. 331412)
Antigen Details
- Structure
- Ig superfamily member, TCR γ/δ with CD3 forms the CD3/TCR complex
- Distribution
-
Expressed on majority of peripheral γ/δT cells
- Function
- Antigen recognition, T cell activation
- Ligand/Receptor
- Peptide bound to MHC
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
-
1. Scotet E, et al. 2005. Immunity 22:71.
2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144. - Gene ID
- 6964 View all products for this Gene ID
- UniProt
- View information about TCR Vdelta2 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human TCR Vδ2
Human peripheral blood lymphocytes stained with purified B6,... -
Biotin anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
FITC anti-human TCR Vδ2
Human peripheral blood lymphocytes stained with CD3 (UCHT1) ... -
PE anti-human TCR Vδ2
Human peripheral blood lymphocytes stained with CD3 (UCHT1) ... -
PerCP anti-human TCR Vδ2
Human peripheral blood lymphocytes stained with CD3 PE and B... -
Brilliant Violet 711™ anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 PE ... -
Pacific Blue™ anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
Alexa Fluor® 700 anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 PE ... -
PerCP/Cyanine5.5 anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
APC anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 Ale... -
PE/Cyanine7 anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
APC/Fire™ 750 anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 Ale... -
Brilliant Violet 421™ anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
Brilliant Violet 605™ anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
PE/Dazzle™ 594 anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
Brilliant Violet 510™ anti-human TCR Vδ2
Human peripheral blood lymphocytes were stained with CD3 APC... -
TotalSeq™-A0582 anti-human TCR Vδ2
-
TotalSeq™-C0582 anti-human TCR Vδ2
-
TotalSeq™-B0582 anti-human TCR Vδ2
-
APC/Cyanine7 anti-human TCR Vδ2
Human peripheral blood mononuclear cells were stained with C... -
Spark Red™ 718 anti-human TCR Vδ2 (Flexi-Fluor™)
-
Spark Blue™ 574 anti-human TCR Vδ2 (Flexi-Fluor™)
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Spark Blue™ 550 anti-human TCR Vδ2 (Flexi-Fluor™)
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