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- Regulatory Status
- RUO
- Other Names
- CGP-39, cartilage glycoprotein-39, GP39, chitinase 3-like 1, CHI3L1
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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ELISA MAX™ Deluxe Set Human YKL-40 Standard Curve
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 479804 | 5 plates | 312€ | ||||
YKL-40, also known as CHI3L1 (Chitinase-3-like protein 1) or cartilage glycoprotein-39 (GP-39) is secreted by chondrocytes, synoviocytes, endothelial cells, smooth muscle cells and immune cells. YKL-40 plays a major role in different physiological processes including cell proliferation, tissue remodeling, angiogenesis, and apoptosis. Elevated serum levels of YKL-40 are linked to the pathogenesis and prognosis of several inflammatory reactions and autoimmune diseases, such as cancer, rheumatoid arthritis, liver cirrhosis, diabetes, and inflammatory bowel disease. Higher YKL-40 levels in cerebral spinal fluid are a known biomarker of brain inflammation and have a potential prognostic utility as a disease-specific marker in neurodegenerative disorders.
Product DetailsKit Contents
- Kit Contents
-
- Human YKL-40 Capture Antibody (200X)
- Human YKL-40 Detection Antibody (200X)
- Human YKL-40 Lyophilized Standard
- Avidin-HRP (1,000X)
- Substrate Solution F
- Coating Buffer B (5X)
- Blocking Buffer A (2X)
- Assay Diluent B (5X)
Product Details
- Verified Reactivity
- Human
- Application
-
ELISA
- As a part of BioLegend's efforts to go green, each new lot of the ELISA MAX™ sets will include a summarized version of its manual. Click here for more information.
- Sensitivity
- 0.43 pg/mL
- Standard Range
- 3.13 – 200 pg/mL
- Materials Not Included
-
- Microwell plates: BioLegend Cat. No. 423501 is recommended
- Wash Buffer: BioLegend Cat. No. 421601 is recommended, or PBS + 0.05% Tween-20
- Stop Solution: BioLegend Cat. No. 423001 is recommended, or acid solution, e.g. 2N H2SO4
- Plate Sealers: BioLegend Cat. No. 423601 is recommended
- PBS (Phosphate-Buffered Saline): 8.0 g NaCl, 1.16 g Na2HPO4, 0.2 g KH2PO4, 0.2 g KCl, add deionized water to 1 L; pH to 7.4, 0.2 μm filtered
- Deionized (DI) water
- A microplate reader capable of measuring absorbance at 450 nm
- Adjustable pipettes to measure volumes ranging from 2 μL to 1 mL
- Wash bottle or automated microplate washer
- Log-Log graph paper or software for data analysis
- Tubes to prepare standard dilutions
- Timer
Antigen Details
- Cell Type
- Dendritic cells, Macrophages
- Biology Area
- Immuno-Oncology, Immunology, Neuroscience
- Molecular Family
- Enzymes and Regulators
- Gene ID
- NA
- UniProt
- View information about YKL 40 on UniProt.org
Related FAQs
- Do the ELISA MAX™ Deluxe Sets come with plates?
-
No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.
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