PE anti-human MUC-17 Antibody, MUC-17, MQ155

Pricing & Availability

Clone: MQ155 (See other available formats)
Regulatory Status: RUO
Other Names: Mucin-17, MUC3, MUC-3
Isotype: Mouse IgG1, κ
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Product Citations: publications

Human pancreatic cancer cell line (AsPC-1) stained with PE MUC-17 (Clone MQ155, filled histogram) or PE mouse IgG1, κ isotype control (open histogram).

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395303

25 tests

128€

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395304

100 tests

292€

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Description

It is a 451 KD glycocylated member of the mucin family with 2 EGF like domains on the C-terminus and serine/tyrosine phosphorylation sites on the cytoplasmic domain. It is expressed by epithelial cells and plays a role in cytoprotection, signal transduction. Expression of this molecule can also render tumor cells to become less adhesive. It interacts with PKDZ1 and increased expression of this molecule has been reported in colon cancer.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Purified recombinant Muc17 protein, Freund’s Complete Adjuvant
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2814359 (BioLegend Cat. No. 395303)
AB_2814359 (BioLegend Cat. No. 395304)

Antigen Details

Structure: 451 KD N-glycosylate single pass membrane protein
Distribution: Gastrointestinal tract
Function: Cytoprotection, extravasation, signal transduction
Interaction: PDZK1
Biology Area: Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity
Antigen References: Malmberg EK, et al. 2008. Biochem J. 410:283.

Gum JR Jr, et al. 2002. Biochem Biophys Res Commun. 291:466.

Hirono S, et al. 2010. Cancer Sci. 101:259.
Gene ID: 140453 View all products for this Gene ID
UniProt: View information about MUC-17 on UniProt.org

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Related Pages & Pathways

Related FAQs

What type of PE do you use in your conjugates?: We use R-PE in our conjugates.

Other Formats

View All MUC-17 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human MUC-17	MQ155	FC
PE anti-human MUC-17	MQ155	FC
APC anti-human MUC-17	MQ155	FC
Alexa Fluor® 647 anti-human MUC-17	MQ155	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 06/28/2019

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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