PE/Dazzle™ 594 anti-human CD110, CD110, S16017A

Pricing & Availability

Clone: S16017A (See other available formats)
Regulatory Status: RUO
Other Names: TPOR, c-MPL, MPLV
Isotype: Mouse IgG2b, κ
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Product Citations: publications

S16017A_PEDazzle594_CD110_Antibody_091918 — Resting human platelets were stained with PE/Dazzle™ 594 anti-human CD110 (clone S16017A; filled histogram) or with PE/Dazzle™ 594 mouse IgG2b, κ isotype control (open histogram).

Compare all formats See PE/Dazzle™ 594 spectral data

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393805

25 tests

141€

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393806

100 tests

306€

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Description

CD110 is a type I transmembrane glycoprotein which functions as a receptor for thrombopoietin; binding causes the proliferation and differentiation of megakaroyocytes in addition to the production of platelets and protection of stem cells from apoptosis. CD110 is primarily expressed on hematopoietic stem cells, hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human CD110 transfectants
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
Excitation Laser: Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2750420 (BioLegend Cat. No. 393805)
AB_2750420 (BioLegend Cat. No. 393806)

Antigen Details

Structure: Type I transmembrane glycoprotein
Distribution: Hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets.
Function: Megakaryocytopoiesis and platelet formation
Interaction: THPO, ATXN2L, JAK2
Ligand/Receptor: Thrombopoietin
Biology Area: Immunology
Molecular Family: CD Molecules
Antigen References: Ninos JM, et al. 2006. J. Transl. Med. 16:4-9.

Broudy VC, et al. 1996. Blood. 88:2026-32.

Wang X, et al. 2016. Blood. 127:3398-409.
Gene ID: 4352 View all products for this Gene ID
UniProt: View information about CD110 on UniProt.org

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Other Formats

View All CD110 Reagents Request Custom Conjugation

Description	Clone	Applications
PE anti-human CD110	S16017A	FC
Purified anti-human CD110	S16017A	FC
Brilliant Violet 421™ anti-human CD110	S16017A	FC
PE/Cyanine7 anti-human CD110	S16017A	FC
APC anti-human CD110	S16017A	FC
PE/Dazzle™ 594 anti-human CD110	S16017A	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 09/19/2018

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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