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KIRAVIA Blue 520™ anti-mouse NK-1.1 Antibody

Pricing & Availability
Clone
S17016D (See other available formats)
Regulatory Status
RUO
Other Names
NKR-P1C, NKR-P1B, Ly-55, CD161b, CD161c
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
S17016D_KVBL520_NK1dot1_Antibody_updated_092321.png
C57BL/6 mouse splenocytes were stained with APC anti-mouse CD49b and KIRAVIA Blue™ 520 anti-mouse NK-1.1 (clone S17016D) (left) or KIRAVIA Blue™ 520 mouse IgG2a, κ isotype control (right).
  • S17016D_KVBL520_NK1dot1_Antibody_updated_092321.png
    C57BL/6 mouse splenocytes were stained with APC anti-mouse CD49b and KIRAVIA Blue™ 520 anti-mouse NK-1.1 (clone S17016D) (left) or KIRAVIA Blue™ 520 mouse IgG2a, κ isotype control (right).
Compare all formats See KIRAVIA Blue 520™ spectral data
Cat # Size Price Quantity Check Availability Save
156521 25 µg 109€
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156522 100 µg 203€
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Description

NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse NK1.1-transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with KIRAVIA Blue 520™ under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.


KIRAVIA Blue™ 520 is a trademark of Sony. This product is subject to proprietary rights of Sony and is made and sold under license from Sony Corporation. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.

Sony and the Sony logo are registered trademarks of Sony Corporation.
Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone S17016D cross-blocks anti-mouse NK1.1 clone PK136, and can stain for NK1.1 post-formaldehyde and methanol-based fixation based on in-house testing.

RRID
AB_2894423 (BioLegend Cat. No. 156521)
AB_2894423 (BioLegend Cat. No. 156522)

Antigen Details

Structure
NKR-P1 gene family
Distribution

NK and NK-T cells in the NK1.1 mouse strains (C57BL, FVB/N, NZB)

Function
NK cell activation, IFN-γ production, cytotoxic granule release
Cell Type
NK cells, NKT cells
Biology Area
Immunology, Innate Immunity
Antigen References
  1. Lanier LL. 1997. Immunity 6:371.
  2. Yokoyama WM, Seaman WE. 1993. Annu. Rev. Immunol. 11:613.
  3. Koo GC, et al. 1986. J. Immunol. 137:3742.
  4. Giorda R, Trucco M. 1991. J. Immunol. 147:1701.
Gene ID
17059 View all products for this Gene ID
UniProt
View information about NK-1.1 on UniProt.org
Go To Top Version: 1    Revision Date: 09-23-2021

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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