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PE/Cyanine7 anti-mouse CD132 (common γ chain) Antibody

Pricing & Availability
Clone
TUGm2 (See other available formats)
Regulatory Status
RUO
Other Names
Common γ chain, γc, IL-2 receptor γ subunit
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
TUGm2_PE-Cyanine7_CD132_Antibody_090622
C57BL/6 splenocytes were stained with anti-mouse CD132 (common γ chain) (clone TUGm2) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram).
  • TUGm2_PE-Cyanine7_CD132_Antibody_090622
    C57BL/6 splenocytes were stained with anti-mouse CD132 (common γ chain) (clone TUGm2) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram).
Compare all formats See PE/Cyanine7 spectral data
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132311 25 µg 132€
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132312 100 µg 287€
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Description

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.06 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References
  1. Kondo M, et al. 1993. Science 262:1874 (Block)
  2. Kondo M, et al. 1994. Science 263:1453
  3. Kimura Y, et al. 1995. Int Immunol. 7:115 (Block)
  4. Veerman KM, et al. 2012. J. Immunol. 188:1638. PubMed.
  5. Hennion-Tscheltzoff O, et al. 2013. Blood. 121:4684. PubMed
RRID
AB_2924467 (BioLegend Cat. No. 132311)
AB_2924467 (BioLegend Cat. No. 132312)

Antigen Details

Structure
Type I transmembrane glycoprotein, Ig superfamily 64-70 kD
Distribution

T cells, B cells, NK, monocytes, granulocytes

Function
Signaling
Ligand/Receptor
Component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21
Cell Type
B cells, Granulocytes, Monocytes, NK cells, T cells
Biology Area
Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References

1. Itano M, et al. 1996. Tohoku J. Exp. Med. 178:389
2. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication
3. Nakarai T, et al. 1994. J. Exp. Med. 180:241
4. Kawahara A, et al. 1995. Proc. Natl. Acad. Sci. USA. 92:8724
5. Habib T, et al. 2002. Biochemistry. 41:8725
6. Matthews DJ, et al. 1995. Blood 85:38

Gene ID
16186 View all products for this Gene ID
UniProt
View information about CD132 on UniProt.org
Go To Top Version: 1    Revision Date: 09-06-2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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