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- Clone
- C15/TCR Vα24 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- TCRAV24S1, TCRAV10
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Peripheral blood lymphocytes were stained with CD3 APC and TCR Va24 (Clone C15/ TCR Va24) PerCP/Cyanine5.5 (left), or mouse IgG1, κ PerCP/Cyanine5.5 isotype control (right).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 360004 | 100 tests | 306€ | ||||
TCR Vα24 is a highly variable region on the TCR which functions in antigen recognition through MHC molecules. TCR Vα24 has been shown to be expressed on a subset of peripheral blood CD3+ lymphocytes. It is also expressed on a population of CD3+CD4-CD8- T cells (invariant NKT cells or iNKT) that produce large amounts of cytokines following stimulation. TCR Vα24 expressing iNKT cells have been reported to be important in immune responses to self and foreign antigens.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human T-cell clone
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm. - Excitation Laser
-
Blue Laser (488 nm)
- Product Citations
-
- RRID
-
AB_2562495 (BioLegend Cat. No. 360004)
Antigen Details
- Structure
- Disulfide-linked 80 kD heterodimer consisting of an α and β chain
- Distribution
-
CD+ invariant NKT cells (iNKT), subset of CD3+ T cells
- Function
- Recognize antigens bound to MHC molecules
- Ligand/Receptor
- Antigen bound MHC molecules
- Cell Type
- NKT cells, T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Antigen References
-
1. Koop BF, et al. 1994. Genomics. 19:478.
2. Kent SC, et al. 1999. Hum. Immunol. 60:1080.
3. Capone M, et al. 2003. J. Immunol. 170:2390. - Gene ID
- 28659 View all products for this Gene ID
- UniProt
- View information about TCR Valpha24 on UniProt.org
Related FAQs
- How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?
-
PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.
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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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