- Clone
- N106/20 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- ANK3, Node Of Ranvier (Ankyrin G), MRT37
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
601252 | 100 µg | 132€ |
Ankryin G is a submembranous scaffold protein expressed in a variety of tissues, including brain, heart, and muscle. In the neurons, Ankyrin G is localized in the axon initial segment and the nodes of Ranvier. Ankyrin G binds to βIV spectrin and actin to create a submembranous cytoskeletal network in axons. By itself, Ankyrin G controls the ion channel clustering and the maintenance of neuronal polarity.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Fusion protein of ~1000 amino acids of Ankyrin-G
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 1.0 µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
This clone was tested for IHC-P and failed.
- RRID
-
AB_2904441 (BioLegend Cat. No. 601252)
Antigen Details
- Structure
- Scaffold protein
- Distribution
-
Axon initial segments and nodes of Ranvier in neurons
- Interaction
- Ion channels
- Antigen References
-
1. Huang C. and Rasband M., 2018. Ann N Y Acad Sci., 1420(1):46-612. Jenkins S. and Bennett V., 2001. J Cell Biol., 155(5):739-7463. Leterrier C. et al., 2017. Front. Cell. Neurosci., 11:
- Gene ID
- 288 View all products for this Gene ID
- UniProt
- View information about Ankyrin G on UniProt.org
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