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- Clone
- SN13 (K5-1B8) (See other available formats)
- Regulatory Status
- RUO
- Other Names
- R1
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human T-lymphoblastic leukemia cell line Molt-4 stained with purified SN13, followed by anti-mouse IgG FITC
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 329102 | 100 µg | 95€ | ||||
CD1b is a 43 kD member of the immunoglobulin superfamily also known as R1. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, CD1c), group II (CD1d), and group III (CD1e). CD1b plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1b has been implicated in thymic T cell development.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Membrane antigen preparation of human thymocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F, IP - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
-
- Hayes SM, et al. 2001. J. Immunol. 166:403. (IF)
- Martin LH, et al. 1987. P. Natl. Acad. Sci. USA 84:918993. (IF)
- Product Citations
-
- RRID
-
AB_961143 (BioLegend Cat. No. 329102)
Antigen Details
- Structure
- immunoglobulin superfamily
- Distribution
-
cortical thymocytes, Langerhans cells, and dendritic cells
- Cell Type
- Dendritic cells, Langerhans cells, Thymocytes, Tregs
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Porcelli S, et al. 1992. Nature 360:5937.
2. Giuliani A, et al. 2001. Infect. Immun. 69:746170. - Gene ID
- 910 View all products for this Gene ID
- UniProt
- View information about CD1b on UniProt.org
Related FAQs
Other Formats
View All CD1b Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD1b | SN13 (K5-1B8) | FC,IHC-F,IP |
| FITC anti-human CD1b | SN13 (K5-1B8) | FC |
| PE anti-human CD1b | SN13 (K5-1B8) | FC |
| APC anti-human CD1b | SN13 (K5-1B8) | FC |
| TotalSeq™-B1468 anti-human CD1b | SN13 (K5-1B8) | PG |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD1b
Human T-lymphoblastic leukemia cell line Molt-4 stained with... -
FITC anti-human CD1b
Human T lymphoblastic leukemia cell line, Molt-4, stained wi... -
PE anti-human CD1b
Human T lymphoblastic leukemia cell line, MOLT-4, stained wi... -
APC anti-human CD1b
Human T lymphoblastic leukemia cell line, Molt-4, were stain... -
TotalSeq™-B1468 anti-human CD1b
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