- Clone
- CD7-6B7 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- IV T-164
- Other Names
- gp40
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
343111 | 100 µg | 113€ |
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- KG1a cell line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1.0 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
CyTOF® - Verified - Recommended Usage
-
This product is suitable for use with the Maxpar® Metal Labeling Kits. For metal labeling using Maxpar® Ready antibodies, proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies.
- Application Notes
-
Additional reported (for the relevant formats) applications include proteogenomics2.
- Additional Product Notes
-
Maxpar® is a registered trademark of Standard BioTools Inc.
- Application References
-
- Knapp W, et al. 1989. Leucocyte Typing IV:White Cell Differentiation Antigens. Oxford University Press.
- Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
- Product Citations
-
- RRID
-
AB_2563761 (BioLegend Cat. No. 343111)
Antigen Details
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 40 kD
- Distribution
-
T cells, NK cells, thymocytes, hematopoietic progenitors, myeloid leukemic cell subsets
- Function
- T cell activation
- Ligand/Receptor
- Cytoplasmic domain associates with P13-kinase
- Cell Type
- Hematopoietic stem and progenitors, Leukemia, NK cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay N, et al. 1993. The Leucocyte Antigen FactsBook. Academic Press Inc. San Diego.
2. Stillwell R, et al. 2001. Immunol. Res. 24:31.
3. Rabinowich H, et al. 1994. J. Immunol. 152:517. - Gene ID
- 924 View all products for this Gene ID
- UniProt
- View information about CD7 on UniProt.org
Related FAQs
- Can I obtain CyTOF data related to your Maxpar® Ready antibody clones?
-
We do not test our antibodies by mass cytometry or on a CyTOF machine in-house. The data displayed on our website is provided by Fluidigm®. Please contact Fluidigm® directly for additional data and further details.
- Can I use Maxpar® Ready format clones for flow cytometry staining?
-
We have not tested the Maxpar® Ready antibodies formulated in solution containing EDTA for flow cytometry staining. While it is likely that this will work in majority of the situations, it is best to use the non-EDTA formulated version of the same clone for flow cytometry testing. The presence of EDTA in some situations might negatively affect staining.
- I am having difficulty observing a signal after conjugating a metal tag to your Maxpar® antibody. Please help troubleshoot.
-
We only supply the antibody and not test that in house. Please contact Fluidigm® directly for troubleshooting advice: http://techsupport.fluidigm.com/
- Is there a difference between buffer formulations related to Maxpar® Ready and purified format antibodies?
-
The Maxpar® Ready format antibody clones are formulated in Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA. The regular purified format clones are formulated in solution that does not contain any EDTA. Both formulations are however without any extra carrier proteins.
Other Formats
View All CD7 Reagents Request Custom ConjugationCompare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CD7
-
FITC anti-human CD7
Human peripheral blood lymphocytes stained with mouse IgG2a,... Human peripheral blood lymphocytes stained with CD7-6B7 FITC... -
PE anti-human CD7
Human peripheral blood lymphocytes stained with CD7 (clone C... -
APC anti-human CD7
Human peripheral blood lymphocytes stained with CD7 (clone C... -
PE/Cyanine5 anti-human CD7
Human peripheral blood lymphocytes stained with CD7-6B7 PE/C... -
PE/Cyanine7 anti-human CD7
Human peripheral blood lymphocytes were stained with CD7 (cl... -
Purified anti-human CD7 (Maxpar® Ready)
Human PBMCs stained with 145Nd-anti-CD4 (RPA-T4) and 147Sm-a... -
PerCP/Cyanine5.5 anti-human CD7
Human peripheral blood lymphocytes were stained with CD7 (cl... -
PE/Dazzle™ 594 anti-human CD7
Human peripheral blood lymphocytes were stained with CD7 (cl... -
APC/Fire™ 750 anti-human CD7
Human peripheral blood lymphocytes were stained with CD7 (cl... -
APC anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
FITC anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
Alexa Fluor® 647 anti-human CD7
Human peripheral blood lymphocytes were stained with CD7 (cl... -
TotalSeq™-A0066 anti-human CD7
-
Alexa Fluor® 700 anti-human CD7
Human peripheral blood lymphocytes were stained with CD7 (cl... -
TotalSeq™-C0066 anti-human CD7
-
PE anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
TotalSeq™-B0066 anti-human CD7
-
Pacific Blue™ anti-human CD7 Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-D0066 anti-human CD7
-
GMP APC anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
GMP FITC anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
PE/Cyanine7 anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
Pacific Blue™ anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
GMP PE anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
PE/Dazzle™ 594 anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
GMP PE/Cyanine7 anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
GMP Pacific Blue™ anti-human CD7
Typical results from human peripheral blood lymphocytes stai... -
Spark NIR™ 685 anti-human CD7
Human peripheral blood lymphocytes were stained with anti-hu... -
GMP PE/Dazzle™ 594 anti-human CD7
Typical results from human peripheral blood lymphocytes stai...
Follow Us