Purified anti-human FGF-basic Antibody

Pricing & Availability
Clone
BHFB15 (See other available formats)
Regulatory Status
RUO
Other Names
Fibroblast Growth Factor-basic, bFGF, FGF-2, FGF2, Heparin-binding growth factor
Isotype
Mouse IgG1, κ
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Product Citations
publications
Cat # Size Price Quantity Check Availability Save
514801 50 µg 85€
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514802 500 µg 226€
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Description

Fibroblast growth factor-basic (also known as FGF-b, FGF-2) is a heparin-binding growth factor, which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal, and endothelial cells. FGF-basic also exerts a potent angiogenic activity in vivo. FGF-basic has been isolated from neural, pituitary, adrenal cortex, and placental tissues. The BHFB15 antibody reacts with human fibroblast growth factor - basic (FGF-basic).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human FGF-basic.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ELISA Capture - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration of 2 µg/ml of the capture antibody was utilized to generate the example standard curve. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

ELISA Capture: The purified BHFB15 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated JKFb-2 antibody as the detecting antibody.

RRID
AB_2561316 (BioLegend Cat. No. 514801)
AB_2561316 (BioLegend Cat. No. 514802)

Antigen Details

Structure
17.2 kD (Mammalian)
Distribution

Brain, retina, pituitary, kidney, placenta, testis, corpus luteum, adrenal glands, monocytes, prostate, bone, liver, cartiliage, endothelial cells, and epithelial cells.

Function
Released after tissue injuries and during the inflammatory process.
Interaction
Fibroblasts, myobalasts, osteoblasts, neuronal cells, endothelial cells, kerintocytes, chrondrocytes, astrocytes, oligodendrocytes, and the smooth muscle.
Ligand/Receptor
FGFR1-1 (flg); FGFR-2 (bek, K-sam); FGFR-4 (flig-2); low affinity coreceptor heparin sulfate, and heparin sulfate proteoglycans required for full activity.
Cell Type
Monocytes, Epithelial cells, Endothelial cells
Biology Area
Angiogenesis, Cell Biology, Immunology, Neuroscience, Synaptic Biology
Molecular Family
Adhesion Molecules, Cytokines/Chemokines, Growth Factors
Antigen References

1. Fitzgerald KA, et al. 2013. The Cytokine Factsbook. Acadmic Press. San Diego.
2. Klagsbrun M, 1992. Semin. Cancer Biol. 3:81.
3. Goldfarb M. 1990. Cell Growth Factor. 1:439.
4. Sensenbrenner M. 1993. Prog. Neurobiol. 6:683.

Gene ID
2247 View all products for this Gene ID
UniProt
View information about FGF-basic on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 01-07-2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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  • Purified anti-human FGF-basic

    Human_FGF-basic_ELISA_RECOM_051117
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