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Purified anti-human TGF-β Receptor II Antibody

Pricing & Availability
Clone
W17055E (See other available formats)
Regulatory Status
RUO
Other Names
TGFRII, TGFR2, TGFR-2, TβRII, TGFbeta-RII, TGF-Beta Receptor Type II, TGF-Beta Receptor Type-2
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
W17055E_PURE_TGF-BR2_Antibody_1_061020
Human peripheral blood lymphocytes were stained with CD3 FITC and TGF-β Receptor II (clone W17055E) purified (left) or rat IgG2b, κ Purified isotype control (right), followed by ant-rat IgG PE.
  • W17055E_PURE_TGF-BR2_Antibody_1_061020
    Human peripheral blood lymphocytes were stained with CD3 FITC and TGF-β Receptor II (clone W17055E) purified (left) or rat IgG2b, κ Purified isotype control (right), followed by ant-rat IgG PE.
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399702 100 µg 278€
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Description

Transforming growth factor beta receptor 2 (TGFbR2 or TGFbRII) forms a heterodimeric complex on the cell surface with TGFbR1. TGFbR2 binds TGF-beta and is important for cell proliferation, wound healing, immunosuppression, and tumorigenesis.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
TGFbR2 protein (aa 1-243) expressing transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2861013 (BioLegend Cat. No. 399702)

Antigen Details

Distribution

B cells, T cells, monocytes, and granulocytes. 

Ligand/Receptor
TGFbR2 forms a heterodimeric complex with TGFbR1 and binds TGF-β.
Cell Type
B cells, Monocytes, T cells
Biology Area
Immunology
Molecular Family
Cytokines/Chemokines
Antigen References
  1. Horbelt D, et al. 2010. J Cell Sci. 123:4340-50.
  2. Wei CY, et al. 2015. Int J Clin Exp Pathol. 8:14619-29.
  3. Numata S, et al. 2008. J Psychiatr Res. 42:425-32.
Gene ID
7048 View all products for this Gene ID
UniProt
View information about TGF-beta Receptor II on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 06-10-2020

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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