Loading...

Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
Ave. Rating
Submit a Review
Product Citations
publications
93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
Compare all formats
Cat # Size Price Quantity Check Availability Save
101301 50 µg 29€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101302 500 µg 92€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  2. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  3. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  4. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  5. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  6. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  7. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  8. Barkaway A, et al. 2021. Immunity. . PubMed
  9. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  10. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  11. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  12. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  13. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  14. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  15. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  16. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  17. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  18. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  19. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  20. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  21. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  22. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  23. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  24. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  25. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  26. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  27. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  28. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  29. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  30. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  31. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  32. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  33. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  34. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  35. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  36. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  37. Miyao T, et al. 2022. Elife. 11: . PubMed
  38. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  39. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  40. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  41. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  42. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  43. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  44. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  45. Akalu YT, et al. 2022. Elife. 11: . PubMed
  46. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  47. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  48. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  49. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  50. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  51. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  52. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  53. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  54. Cousin N, et al. 2022. Cells. 12: . PubMed
  55. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  56. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  57. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  58. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  59. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  60. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  61. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  62. Liu X, et al. 2022. Pain. 163:508. PubMed
  63. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  64. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  65. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  66. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  67. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  68. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  69. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  70. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  71. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  72. Ding P, et al. 2022. Elife. 11:. PubMed
  73. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  74. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  75. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  76. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  77. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  78. Li L, et al. 2023. iScience. 26:106095. PubMed
  79. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  80. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  81. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  82. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  83. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  84. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  85. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  86. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  87. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  88. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  89. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  90. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  91. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  92. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  93. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  94. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  95. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  96. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  97. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  98. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  99. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  100. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  101. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  102. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  103. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  104. Mevel R, et al. 2020. eLife. 9:00. PubMed
  105. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  106. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  107. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  108. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  109. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  110. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  111. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  112. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  113. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  114. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  115. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  116. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  117. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  118. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  119. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  120. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  121. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  122. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  123. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  124. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  125. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  126. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  127. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  128. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  129. Goel S, et al. 2017. Nature. 548:471. PubMed
  130. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  131. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  132. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  133. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  134. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  135. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  136. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  137. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  138. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  139. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  140. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  141. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  142. Feng J, et al. 2021. iScience. 24:103004. PubMed
  143. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  144. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  145. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  146. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  147. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  148. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  149. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  150. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  151. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  152. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  153. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  154. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  155. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  156. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  157. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  158. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  159. Diao L, et al. 2022. iScience. 25:105511. PubMed
  160. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  161. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  162. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  163. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  164. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  165. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  166. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  167. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  168. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  169. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  170. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  171. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  172. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  173. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  174. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  175. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  176. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  177. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  178. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  179. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  180. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  181. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  182. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  183. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  184. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  185. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  186. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  187. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  188. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  189. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  190. Tal MC, et al. 2020. MBio. 11:00. PubMed
  191. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  192. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  193. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  194. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  195. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  196. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  197. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  198. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  199. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  200. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  201. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  202. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  203. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  204. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  205. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  206. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  207. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  208. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  209. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  210. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  211. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  212. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  213. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  214. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  215. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  216. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  217. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  218. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  219. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  220. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  221. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  222. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  223. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  224. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  225. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  226. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  227. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  228. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  229. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  230. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  231. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  232. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  233. Wong HS, et al. 2021. Cell. . PubMed
  234. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  235. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  236. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  237. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  238. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  239. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  240. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  241. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  242. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  243. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  244. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  245. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  246. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  247. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  248. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  249. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  250. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  251. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  252. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  253. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  254. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  255. Baasch S, et al. 2021. Cell. . PubMed
  256. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  257. Zheng J, et al. 2020. bioRxiv. . PubMed
  258. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  259. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  260. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  261. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  262. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  263. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  264. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  265. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  266. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  267. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  268. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  269. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  270. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  271. Xu S, et al. 2021. Immunity. . PubMed
  272. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  273. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  274. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  275. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  276. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  277. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  278. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  279. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  280. Roy K, et al. 2019. Immunity. 50:616. PubMed
  281. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  282. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  283. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  284. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  285. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  286. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  287. Welte T, et al. 2021. iScience. 24:103349. PubMed
  288. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  289. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  290. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  291. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  292. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  293. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  294. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  295. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  296. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  297. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  298. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  299. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  300. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  301. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  302. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  303. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  304. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  305. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  306. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  307. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  308. Zheng J, et al. 2020. Nature. . PubMed
  309. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  310. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  311. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  312. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  313. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  314. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  315. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  316. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  317. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  318. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  319. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  320. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  321. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  322. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  323. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  324. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  325. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  326. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  327. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  328. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  329. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  330. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  331. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  332. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  333. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  334. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  335. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  336. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  337. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  338. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  339. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  340. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  341. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  342. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  343. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  344. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  345. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  346. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  347. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  348. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  349. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  350. Lenert R 2005. J Immunol. 174:2429. PubMed
  351. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  352. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  353. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  354. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  355. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  356. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  357. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  358. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  359. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  360. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  361. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  362. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  363. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  364. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  365. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  366. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  367. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  368. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  369. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  370. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  371. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  372. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  373. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  374. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  375. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  376. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  377. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  378. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  379. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  380. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  381. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  382. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  383. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  384. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  385. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  386. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  387. William M, et al. 2018. J Immunol. 200:4102. PubMed
  388. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  389. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  390. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  391. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  392. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  393. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  394. Lee SA, et al. 2021. Cells. 10:. PubMed
  395. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  396. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  397. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  398. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  399. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  400. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  401. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  402. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  403. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  404. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  405. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  406. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  407. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  408. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  409. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  410. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  411. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  412. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  413. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  414. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  415. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  416. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  417. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  418. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  419. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  420. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  421. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  422. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  423. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  424. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  425. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  426. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  427. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  428. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  429. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  430. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  431. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  432. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  433. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  434. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  435. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  436. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  437. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  438. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  439. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  440. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  441. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  442. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  443. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  444. Sibler E, et al. 2021. Cells. 10:. PubMed
  445. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  446. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  447. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  448. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  449. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  450. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  451. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  452. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  453. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  454. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  455. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  456. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  457. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312800 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org
Go To Top Version: 2    Revision Date: 01-23-2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account