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- Clone
- S21016C (See other available formats)
- Regulatory Status
- RUO
- Other Names
- T10
- Isotype
- Rat IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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C57BL/6 mouse splenocytes were stained with purified anti-mouse CD38 (clone S21016C) or purified rat IgG1, κ isotype control followed by goat anti-rat IgG PE. Cells were costained with anti-mouse B220 APC.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 116902 | 100 µg | 88€ | ||||
CD38, also known as T10, is a 45 kD type II transmembrane glycoprotein. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is thought to be a ligand of CD38.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse CD38 transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
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Clone S21016C can completely block the binding of clone “90” on target cells.
- RRID
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AB_3068186 (BioLegend Cat. No. 116902)
Antigen Details
- Structure
- ADP-ribosyl hydrolase, 42 kD
- Distribution
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B cells, NK cells, T cell subset, brain, muscle, kidney
- Function
- Regulation of cellular activation/proliferation, adhesion, metabolism of cADPR and NAADP
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- B cells, Lymphocytes, NK cells, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Immuno-Oncology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
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- Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
- Shubinsky G, et al. 1997. Immunity. 7:315-24.
- Cesano A, et al. 1998. J Immunol. 160:1106-15.
- Cockayne DA, et al. 1998. Blood. 92:1324-33.
- Gene ID
- 12494 View all products for this Gene ID
- UniProt
- View information about CD38 on UniProt.org
Related FAQs
Other Formats
View All CD38 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse CD38 | S21016C | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD38
C57BL/6 mouse splenocytes were stained with purified anti-mo...
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