Loading...

PerCP/Cyanine5.5 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
30-F11_PerCPCyanine55_CD45_Antibody_082418
C57BL/6 mouse splenocytes were stained with CD45 (Clone 30-F11) PerCP/Cyanine5.5 (filled histogram), or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (open histogram).
  • 30-F11_PerCPCyanine55_CD45_Antibody_082418
    C57BL/6 mouse splenocytes were stained with CD45 (Clone 30-F11) PerCP/Cyanine5.5 (filled histogram), or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (open histogram).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
103131 25 µg 70€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
103132 100 µg 177€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Choi JG, et al. 2020. Front Immunol. 11:598556. PubMed
  2. Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
  3. Daemen S, et al. 2021. Cell Reports. 34(2):108626. PubMed
  4. Zaman R, et al. 2021. Immunity. :. PubMed
  5. Ramakrishna C, et al. 2019. Nat Commun. 10:2153. PubMed
  6. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  7. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  8. Pani F, et al. 2021. Endocrinology. 162:. PubMed
  9. Xuan W, et al. 2022. Cancer Immunol Res. 10:770. PubMed
  10. Liu W, et al. 2022. Biomedicines. 10: . PubMed
  11. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  12. Wu X, et al. 2022. J Clin Med. 11: . PubMed
  13. Xie DH, et al. 2022. Med Phys. 49:6728. PubMed
  14. Poh AR, et al. 2022. Cell Rep. 41:111479. PubMed
  15. VanDyke D, et al. 2022. Cell Rep. 41:111478. PubMed
  16. Mansouri S, et al. 2022. J Immunol. 209:2114. PubMed
  17. Lai C, et al. 2023. J Bone Miner Res. 38:86. PubMed
  18. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  19. Xu H, et al. 2022. Aging Dis. 13:1875. PubMed
  20. Zha AH, et al. 2022. Lupus Sci Med. 9: . PubMed
  21. Guo J, et al. 2023. Cell Rep Med. 4:100881. PubMed
  22. Yang L, et al. 2023. Acta Pharmacol Sin. :. PubMed
  23. Liu G, et al. 2023. Commun Biol. 6:102. PubMed
  24. Chan L, et al. 2023. Int J Mol Sci. 24: . PubMed
  25. Kuehm LM, et al. 2021. Cancer Immunol Res. 9:227. PubMed
  26. Khan NZ, et al. 2021. Brain Behav Immun. 92:165. PubMed
  27. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  28. Tang Y, et al. 2022. Dev Cell. 57:480. PubMed
  29. Li X, et al. 2022. Cell. 185:1709. PubMed
  30. Xiong W, et al. 2022. Nat Commun. 13:1700. PubMed
  31. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  32. Jung IY, et al. 2022. Sci Transl Med. 14:eabn7336. PubMed
  33. Zhang Q, et al. 2022. Nat Metab. 4:1055. PubMed
  34. Bermea KC, et al. 2022. J Vis Exp. . PubMed
  35. Bajaj R, et al. 2022. Cell Rep. 40:111429. PubMed
  36. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  37. Axelrod ML, et al. 2022. Nature. 611:818. PubMed
  38. Pagni RL, et al. 2022. Front Immunol. 13:1005937. PubMed
  39. Fei F, et al. 2022. Int J Mol Sci. 23:. PubMed
  40. Shi H, et al. 2022. Nutrients. 14:. PubMed
  41. Li J, et al. 2022. Elife. 11:. PubMed
  42. Matsuzawa M, et al. 2023. Nat Commun. 14:1417. PubMed
  43. Xiao Y, et al. 2023. EMBO J. 42:e111762. PubMed
  44. He Y, et al. 2023. Biomolecules. 13:. PubMed
  45. Zhang Z, et al. 2023. Aging Dis. 14:966. PubMed
  46. Doloff JC, et al. 2023. Sci Adv. 9:eade9488. PubMed
  47. Krausgruber T, et al. 2020. Nature. 583:296. PubMed
  48. Kawano H, et al. 2016. Int Immunol. 28: 489 - 501. PubMed
  49. Liu W, et al. 2020. Mol Ther Oncolytics. 17:350. PubMed
  50. Yang H, et al. 2019. Mol Metab. 23:24. PubMed
  51. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  52. Tan L, et al. 2022. Biochem Biophys Rep. 32:101351. PubMed
  53. Padonou F, et al. 2022. EMBO Rep. 23:e53576. PubMed
  54. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  55. Taddeo A, et al. 2022. NPJ Vaccines. 7:82. PubMed
  56. Li Y, et al. 2022. Int J Biol Sci. 18:3697. PubMed
  57. Tatsuguchi T, et al. 2022. Int Immunol. 34:277. PubMed
  58. Li Z, et al. 2021. Immunology. 163:105. PubMed
  59. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  60. Rodda LB et al. 2018. Immunity. 48(5):1014-1028 . PubMed
  61. Barry KC, et al. 2018. Nat Med. 24:1178. PubMed
  62. Hsu SPC, et al. 2020. J Neurooncol. 146:417. PubMed
  63. Yang M, et al. 2020. Cell Prolif. 53:e12784. PubMed
  64. Hanhai Z, et al. 2021. Aging (Albany NY). 13:13108. PubMed
  65. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  66. Sasse C, et al. 2022. Pathogens. 11:. PubMed
  67. Coleby R, et al. 2021. Clin Exp Rheumatol. :39. PubMed
  68. Garcia–Agudo LF, et al. 2019. FASEB J. :fj201900337R. PubMed
  69. Zaytseva D, et al. 2018. Physiol Rep. 6:e13812. PubMed
  70. Schmidleithner L et al. 2019. Immunity. 50(5):1232-1248 . PubMed
  71. Biffi G, et al. 2018. Cancer Discov. 2:282. PubMed
  72. Jazowiecka-Rakus J, et al. 2021. Cancers (Basel). 13:. PubMed
  73. Ren J, et al. 2021. Theranostics. 11:304. PubMed
  74. Craver BM, et al. 2020. Blood Adv. 4:312. PubMed
  75. Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
  76. Peng Z, et al. 2021. STAR Protocols. 2(2):100595. PubMed
  77. Jeong D, et al. 2021. eLife. 0.416666666666667. PubMed
  78. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  79. Damal Villivalam S, et al. 2020. Nat Commun. 4313:11. PubMed
  80. Chaurasiya S, et al. 2020. Oncoimmunology. 9:1729300. PubMed
  81. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  82. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
  83. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  84. Potluri HK, et al. 2022. J Immunother Cancer. 10:. PubMed
  85. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  86. Liang Z, et al. 2021. J Cell Physiol. 236:4725. PubMed
  87. Fernandez Garcia-Agudo L, et al. 2021. Cell Rep. 36:109548. PubMed
  88. Chung H, et al. 2021. Immune Netw. 21:e28. PubMed
  89. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  90. Wang C, et al. 2021. Cell Stem Cell. . PubMed
  91. Fachi JL, et al. 2020. J Exp Med. 217:00:00. PubMed
  92. Sakaguchi M, et al. 2022. Nat Commun. 13:6092. PubMed
  93. Chimenti I, et al. 2022. Cell Death Discov. 8:149. PubMed
  94. Liu Y, et al. 2022. Nat Commun. 13:2665. PubMed
  95. Vijay R, et al. 2015. J Exp Med. 212: 1851 - 1868. PubMed
  96. Fleury M, et al. 2015. Development. 142: 3307 - 3320. PubMed
  97. Osborne JK, et al. 2021. Cell Reports. 36(3):109408. PubMed
  98. Wei SC, et al. 2020. Cancer Discov. . PubMed
  99. Vasilijevic J, et al. 2017. PLoS Pathog. 13:e1006650. PubMed
  100. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  101. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  102. Alexander RK, et al. 2020. eLife. 9:e54090.. PubMed
  103. Voisin M, et al. 2021. Commun Biol. 4:420. PubMed
  104. Edwards CJ, et al. 2021. Br J Cancer. . PubMed
  105. Peres-Emidio EC, et al. 2022. Front Cell Infect Microbiol. 12:811474. PubMed
  106. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  107. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  108. Nicholas DA, et al. 2020. Scientific Reports. 10(1):13063. PubMed
  109. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  110. Linde N, et al. 2018. Nat Commun. 9:21. PubMed
  111. Wang W, et al. 2022. Aging Cell. 21:e13630. PubMed
  112. Lee J, et al. 2022. Nat Commun. 13:1516. PubMed
  113. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  114. Li Z, et al. 2022. J Exp Clin Cancer Res. 41:74. PubMed
  115. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  116. Li N, et al. 2021. eLife. 10:00. PubMed
  117. Zhao J, et al. 2018. Stem Cell Reports. 10:180. PubMed
  118. Wu Y, et al. 2021. Nat Commun. 12:2346. PubMed
  119. Shi R, et al. 2022. Theranostics. 12:875. PubMed
  120. Akazawa S, et al. 2021. Diabetologia. 64:878. PubMed
  121. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  122. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  123. Witkowski MT, et al. 2020. Cancer Cell. 37:867. PubMed
  124. Hu Y, et al. 2021. Bioact Mater. 2905:6. PubMed
  125. Wen Y, et al. 2020. Hypertension. 869:75. PubMed
  126. Hsu CY, et al. 2020. Frontiers in Immunology. 11:574839. PubMed
  127. Bayik D, et al. 2020. Cancer Discov. 1.256944444. PubMed
  128. Horiguchi H, et al. 2019. Genes Dev. 33:1641. PubMed
  129. Adrover JM et al. 2019. Immunity. 50(2):390-402 . PubMed
  130. Christ A, et al. 2018. Cell. 172:162. PubMed
  131. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  132. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  133. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  134. Yang Z, et al. 2021. Sci Adv. 7:. PubMed
  135. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  136. Myerson JW, et al. 2021. Nat Nanotechnol. Online ahead of print. PubMed
  137. Liu Z, et al. 2015. Development. 142: 2452 - 2463. PubMed
  138. Wang Y, et al. 2020. Cell Death Dis. 1.169444444. PubMed
  139. Sharma M, et al. 2020. Circ Res. 127:335. PubMed
  140. Shao M, et al. 2021. Cell Stem Cell. 28(4):685-701.e7. PubMed
  141. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  142. Du Q et al. 2019. Dev Cell. 49(4):618-631 . PubMed
  143. Branchett WJ, et al. 2020. Wellcome Open Research. 0.278472222. PubMed
  144. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  145. Krueger A, et al. 2022. Front Microbiol. 12:789042. PubMed
  146. Mittal A, et al. 2021. Sci Rep. 11:10731. PubMed
  147. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  148. Weinstock A, et al. 2021. Elife. :10. PubMed
  149. Joffin N, et al. 2021. Cell Stem Cell. 28(4):702-717.e8. PubMed
  150. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  151. Ballesteros I, et al. 2020. Cell. 183(5):1282-1297.e18. PubMed
  152. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  153. Sun L, et al. 2015. Sci Rep. 5: 14871. PubMed
  154. Timblin GA, et al. 2021. Nat Metab. 3:618. PubMed
  155. Otvos B, et al. 2021. Clin Cancer Res. 27:2038. PubMed
  156. Lang V, et al. 2021. Elife. 10:. PubMed
  157. Toth K, et al. 2022. PLoS Biol. 20:e3001526. PubMed
  158. Chandra J, et al. 2016. Immunol Cell Biol. 10.1038/icb.2016.83. PubMed
  159. Uematsu T, et al. 2016. Sci Rep. 6:37815. PubMed
  160. Alam Z, et al. 2020. Cell Rep. 107825:31. PubMed
  161. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  162. Li CJ, et al. 2018. J Clin Invest. 128:5251. PubMed
  163. Tao Z, et al. 2019. Clin Cancer Res. 25:1113. PubMed
  164. Zhang Q, et al. 2021. Front Cell Dev Biol. 9:655552. PubMed
  165. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  166. Thomas K, et al. 2022. JCI Insight. :. PubMed
  167. Xu X, et al. 2022. EMBO Rep. 23:e53509. PubMed
  168. Gomez S, et al. 2022. J Immunother Cancer. 10:. PubMed
  169. Shan B, et al. 2020. Nat Metab. 1332:2. PubMed
  170. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  171. Martomo SA, et al. 2021. Mol Cancer Ther. 1.074305556. PubMed
  172. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  173. Ngamsri KC, et al. 2020. Front Immunol. 11:407. PubMed
  174. Haider N, et al. 2020. Cell Commun Signal. 18:26. PubMed
  175. Bernstock JD, et al. 2019. J Allergy Clin Immunol. 145:358. PubMed
  176. Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
  177. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  178. Li M, et al. 2021. Cancers (Basel). 13:. PubMed
  179. Dong X, et al. 2022. Front Immunol. 13:896472. PubMed
  180. Pizzurro GA, et al. 2021. Cancers (Basel). 13:. PubMed
  181. Olson B, et al. 2021. Brain Behav Immun. 97:102. PubMed
  182. Calle P, et al. 2021. Cells. 10:. PubMed
  183. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  184. Yu M, et al. 2021. Molecular Cell. 81(6):1216-1230.e9. PubMed
  185. Zhang H, et al. 2021. Cell Reports. 35(6):109096. PubMed
  186. Ko HJ, et al. 2020. Front Immunol. 1897:11. PubMed
  187. Klose A, et al. 2018. JCSM Rapid Commun. 9:20222. PubMed
  188. Casanova-Acebes M, et al. 2018. J Exp Med. 215:2778. PubMed
  189. Chiang N, et al. 2019. J Clin Invest. 129:5294. PubMed
  190. Scott NA, et al. 2018. Front Immunol. 2.319444444. PubMed
  191. Karolin A, et al. 2022. Front Pharmacol. 12:789080. PubMed
  192. Jazowiecka-Rakus J, et al. 2020. Mol Ther Oncolytics. 18:335. PubMed
  193. Wong NR, et al. 2021. Immunity. 54:2072. PubMed
  194. Mesnieres M, et al. 2021. Cell Reports. 36(8):109618. PubMed
  195. Doss PMIA, et al. 2021. Cell Reports. 34(10):108833. PubMed
  196. Caporarello N, et al. 2020. Aging Cell. 19:e13196. PubMed
  197. Huo M, et al. 2017. FASEB J. 10.1096/fj.201601030R. PubMed
  198. Moufarrij S, et al. 2020. Sci Rep. 10:3470. PubMed
  199. Böhm AM et al. 2019. Dev Cell. 51(2):236-254 . PubMed
  200. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  201. Mello AM, et al. 2022. Oncogenesis. 11:56. PubMed
  202. Shaikh H, et al. 2021. Front Immunol. 12:689896. PubMed
  203. Sánchez-del-Campo L, et al. 2021. J Exp Clin Cancer Res. 40:117. PubMed
  204. Steele NG, et al. 2021. Clin Cancer Res. 27:2023. PubMed
  205. Casselli T, et al. 2021. PLoS Pathog. 17:e1009256. PubMed
  206. Patel K, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.11. PubMed
  207. Tsunekuni K, et al. 2020. J Clin Med. 9:00. PubMed
  208. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  209. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  210. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  211. Baron CS, et al. 2018. Nat Commun. 9:2517. PubMed
  212. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  213. Miragaia RJ, et al. 2018. Sci Rep. 8:685. PubMed
  214. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  215. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  216. Yu H, et al. 2021. Cell Death Dis. 13:1. PubMed
  217. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  218. Zhang Z, et al. 2020. Nature. 579:415. PubMed
  219. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  220. Liu SS, et al. 2021. Immunity. :. PubMed
  221. Wang Y, et al. 2021. Nat Commun. 0.570833333. PubMed
  222. Gao P, et al. 2020. Front Immunol. 1.636111111. PubMed
  223. Sharma M, et al. 2019. Immunometabolism. 1. PubMed
  224. Liang Z, et al. 2017. Autophagy. 14:505. PubMed
  225. Rosen SF, et al. 2022. Genome Med. 14:108. PubMed
  226. Schulze J, et al. 2021. Stroke. 52:2939. PubMed
  227. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  228. Garcia-Alegria E, et al. 2016. Sci Rep. 6: 25917. PubMed
  229. Kim SI, et al. 2020. Molecular Cancer Therapeutics. 20(1):173-182. PubMed
  230. Durga Devi T, et al. 2017. Am J Pathol. 187:2659. PubMed
  231. Wang L, et al. 2020. Nat Commun. 0.654166667. PubMed
  232. Hsu HP, et al. 2021. J Biol Chem. 296:100419. PubMed
  233. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  234. Chen Y, et al. 2021. Braz J Med Biol Res. 54:e9570. PubMed
  235. Caporarello N, et al. 2022. Nat Commun. 13:4170. PubMed
  236. Deptuch T, et al. 2022. Sci Rep. 12:13480. PubMed
  237. Omori S, et al. 2020. Cell Metabolism. 32(5):814-828.e6. PubMed
  238. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  239. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  240. Mitchell LA, et al. 2019. Oncotarget. 10:2252. PubMed
  241. Han Y, et al. 2019. J Clin Invest. 130:26. PubMed
  242. Riopel M, et al. 2019. Mol Metab. 20:89. PubMed
  243. Wirasinha RC, et al. 2021. J Exp Med. 218: . PubMed
  244. Liang Z, et al. 2022. iScience. 25:105233. PubMed
  245. Vogiatzi A, et al. 2021. Mol Cell Biol. 41:e0014921. PubMed
  246. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  247. Li X, et al. 2021. Front Immunol. 12:779560. PubMed
  248. Sheriff L, et al. 2020. Dis Model Mech. 13:dmm046383. PubMed
  249. Zheng QY, et al. 2020. FASEB J. 34:10590. PubMed
RRID
AB_893340 (BioLegend Cat. No. 103131)
AB_893340 (BioLegend Cat. No. 103132)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD45
Specificity Alt (DOES NOT SHOW ON TDS):
CD45
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about CD45 on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Go To Top Version: 3    Revision Date: 08.24.2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account