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PerCP/Cyanine5.5 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
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Product Citations
publications
M1slash70_PerCPCyanine55_CD11b_Antibody_111918
C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
  • M1slash70_PerCPCyanine55_CD11b_Antibody_111918
    C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
101227 25 µg 72€
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101228 100 µg 234€
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Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  2. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  3. Grandjean CL, et al. 2021. Sci Adv. 7:. PubMed
  4. Leslie J, et al. 2021. Sci Rep. 11:1415. PubMed
  5. Zheng J, et al. 2022. Front Pharmacol. 13:866228. PubMed
  6. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  7. Tian WJ, et al. 2021. Clin Exp Pharmacol Physiol. 48:902. PubMed
  8. Ferrao Blanco MN, et al. 2022. Br J Pharmacol. 179:2771. PubMed
  9. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  10. Agarwalla P, et al. 2022. Nat Biotechnol. 40:1250. PubMed
  11. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  12. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  13. Marquardt RM, et al. 2022. Int J Mol Sci. 23: . PubMed
  14. Halin C, et al. 2022. EMBO J. 41:e111528. PubMed
  15. Auguste YSS, et al. 2022. Nat Neurosci. 25:1273. PubMed
  16. Schepers M, et al. 2023. Brain Behav Immun. 109:1. PubMed
  17. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  18. Glaubitz J, et al. 2023. Gut. :. PubMed
  19. Zhang K, et al. 2023. Nat Metab. 5:129. PubMed
  20. Arimoto KI, et al. 2023. Nat Commun. 14:251. PubMed
  21. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  22. Lazure F, et al. 2023. Nat Commun. 14:535. PubMed
  23. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  24. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  25. Drummer C, et al. 2023. Front Immunol. 14:1113883. PubMed
  26. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  27. Wilden A, et al. 2022. Front Immunol. 13:991295. PubMed
  28. Lee T, et al. 2014. Mol Biol Cell. 25:583. PubMed
  29. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  30. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  31. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  32. Peng W, et al. 2022. Cell Mol Life Sci. 79:602. PubMed
  33. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  34. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  35. Guo D, et al. 2023. Cell Biosci. 13:51. PubMed
  36. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  37. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  38. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  39. Haensel D, et al. 2023. Nat Commun. 14:2685. PubMed
  40. Milasan A, et al. 2017. J Am Heart Assoc. 10.1161/JAHA.117.006892. PubMed
  41. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  42. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  43. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  44. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  45. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  46. Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
  47. Hong M, et al. 2021. Int J Mol Sci. 22:. PubMed
  48. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  49. Zhao X, et al. 2022. Front Mol Biosci. 9:786864. PubMed
  50. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  51. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  52. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  53. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  54. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
  55. Kaczanowska S, et al. 2021. Cell. 184(8):2033-2052.e21. PubMed
  56. John S, et al. 2020. Sci Rep. 10:11377. PubMed
  57. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  58. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  59. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  60. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  61. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  62. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
  63. Dong L, et al. 2021. Cancer Cell. . PubMed
  64. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  65. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
  66. Chen L, et al. 2019. Cell Mol Gastroenterol Hepatol. 7:623. PubMed
  67. Kenichi Shimada et al. 2018. Immunity. 49(5):873-885 . PubMed
  68. Kobayashi T, et al. 2019. Cell. 176:982. PubMed
  69. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  70. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  71. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  72. Biswas S, et al. 2021. Nature. 591:464. PubMed
  73. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  74. Yuan Q, et al. 2021. Cell Reports. 34(5):108724. PubMed
  75. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  76. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  77. Sun P, et al. 2015. J Hepatol. . PubMed
  78. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  79. Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed
  80. Cai B, et al. 2021. Mol Cancer. 20:165. PubMed
  81. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  82. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  83. Galle E, et al. 2022. Genome Biol. 23:207. PubMed
  84. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  85. Neubert K, et al. 2014. J Immunol. 192:5830. PubMed
  86. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  87. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  88. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  89. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  90. Jiao H, et al. 2021. Cell. 184(11):2896-2910.e13. PubMed
  91. Lu S, et al. 2020. JCI Insight. 5:00. PubMed
  92. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  93. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  94. Jeong SJ, et al. 2021. Autophagy. 17:3740. PubMed
  95. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  96. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  97. Plein A, et al. 2018. Nature. 562:223. PubMed
  98. Xu G, et al. 2022. Cell Death Dis. 13:888. PubMed
  99. Raineri D, et al. 2021. Biomedicines. 10:. PubMed
  100. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  101. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  102. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  103. Nishi C, et al. 2014. Mol Cell Biol. 34:1512. PubMed
  104. Fulham MA, et al. 2019. Am J Physiol Cell Physiol. 317:C687. PubMed
  105. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  106. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  107. Lu CY, et al. 2020. J Neurosci. 40:9602. PubMed
  108. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  109. Qian SJ, et al. 2021. Front Immunol. 12:711337. PubMed
  110. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  111. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  112. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  113. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  114. Yu Y, et al. 2022. Nat Commun. 13:6857. PubMed
  115. Bretscher P, et al. 2015. EMBO Mol Med. 7:593. PubMed
  116. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  117. Qi T, et al. 2020. Cell Rep. 33:108452. PubMed
  118. Bogie JF, et al. 2020. Ther Adv Chronic Dis. 11:2040622320947378. PubMed
  119. Nayak RR, et al. 2021. Cell Host Microbe. 29(3):362-377.e11. PubMed
  120. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  121. Yue X, et al. 2019. Nat Commun. 10:2011. PubMed
  122. Pereira JA, et al. 2020. Hum Mol Genet. 29:1253. PubMed
  123. Wei W, et al. 2022. mSystems. 7:e0046922. PubMed
  124. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  125. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  126. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  127. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  128. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  129. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  130. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  131. Lu S, et al. 2020. Arterioscler Thromb Vasc Biol. 40:394. PubMed
  132. Sun L, et al. 2015. J Immunol. 194:4891. PubMed
  133. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  134. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  135. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  136. Carbone C, et al. 2021. J Immunother Cancer. 9:. PubMed
  137. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  138. Anger-Góra N, et al. 2021. Oncol Lett. 22:582. PubMed
  139. Sharma A, et al. 2020. Cell. 183(2):377-394.e21. PubMed
  140. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  141. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  142. Sasaki T, et al. 2020. Cell Reports. 28(1):202-217.e7.. PubMed
  143. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  144. Wu S, et al. 2022. BMC Immunol. 23:17. PubMed
  145. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  146. Zhao D, et al. 2020. Cancer Discov. 10:1374. PubMed
  147. Cruz-Herranz A, et al. 2021. JCI Insight. 6: . PubMed
  148. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  149. Stowe CL, et al. 2019. eLife. 0.333333333333333. PubMed
  150. Chatterjee D, et al. 2021. Cell Reports. 35(2):108996. PubMed
  151. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  152. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  153. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  154. Lin W, et al. 2019. EBioMedicine. 49:133. PubMed
  155. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  156. Brown SM et al. 2017. Endocrinology. 158(10):3592-3604 . PubMed
  157. López MJ, et al. 2018. Invest Ophthalmol Vis Sci. 59:5671. PubMed
  158. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  159. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  160. Chruewkamlow N, et al. 2021. Stem Cell Res Ther. 12:520. PubMed
  161. Vachon L, et al. 2022. Theranostics. 12:1440. PubMed
  162. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  163. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  164. Ni C, et al. 2021. Infect Immun. 89:. PubMed
  165. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  166. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  167. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  168. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  169. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  170. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
  171. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  172. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  173. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  174. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  175. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  176. Guo D, et al. 2022. Bone Res. 10:45. PubMed
  177. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  178. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  179. Dulken BW, et al. 2019. Nature. 571:205. PubMed
  180. Muri J, et al. 2020. eLife. 9:e53627.. PubMed
  181. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  182. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  183. Hightower RM, et al. 2019. Mol Ther. 28:189. PubMed
  184. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  185. Bitschar K, et al. 2019. Nat Commun. 10:2730. PubMed
  186. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  187. Unsinger J, et al. 2021. J Leukoc Biol. 109:697. PubMed
  188. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  189. Bennett FC, et al. 2018. Neuron. 98:1170. PubMed
  190. Yang X, et al. 2018. Sci Rep. 8:188. PubMed
  191. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  192. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  193. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  194. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  195. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  196. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  197. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  198. Xu JL, et al. 2022. Front Pharmacol. 13:911663. PubMed
  199. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  200. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  201. Gu H, et al. 2021. Elife. 10:. PubMed
  202. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  203. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  204. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  205. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  206. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  207. Liao Y, et al. 2020. Theranostics. 7.113888889. PubMed
  208. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  209. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  210. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  211. Tothova Z et al. 2017. Cell stem cell. 21(4):547-555 . PubMed
  212. Werner A, et al. 2021. iScience. 24:103076. PubMed
  213. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  214. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  215. Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-00654-2. PubMed
  216. Danzer H, et al. 2020. Elife. 9:00. PubMed
  217. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  218. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  219. Molgora M, et al. 2020. Cell. 182:886. PubMed
  220. Starr T, et al. 2018. PLoS One. 13:e0193601. PubMed
  221. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  222. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  223. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  224. Jaitin DA et al. 2016. Cell. 167(7):1883-1896 . PubMed
  225. Zhang J, et al. 2018. Oncoimmunology. 7:e1461301. PubMed
  226. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  227. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  228. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  229. Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
  230. Tummala G, et al. 2021. Invest Ophthalmol Vis Sci. 62:41. PubMed
  231. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  232. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  233. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  234. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  235. Guey B, et al. 2014. Proc Natl Acad Sci U S A. 111:17254. PubMed
  236. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  237. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  238. Bohlen CJ et al. 2017. Neuron. 94(4):759-773 . PubMed
  239. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  240. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  241. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  242. Tripathi A, et al. 2021. Mol Psychiatry. 26:3043. PubMed
  243. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  244. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  245. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  246. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  247. Lee J, et al. 2015. Nat Commun. 6: 8499. PubMed
  248. Sen D, et al. 2016. PLoS One. 11:e0165064. PubMed
  249. Liddelow S, et al. 2017. Nature. 541:481-487. PubMed
  250. Xu Z, et al. 2020. Cell Rep. 32:108041. PubMed
  251. Ang QY, et al. 2020. Cell. 181(6):1263-1275.e16. PubMed
  252. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  253. Koyama M et al. 2019. Immunity. 51(5):885-898 . PubMed
  254. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  255. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  256. Erens C, et al. 2022. Biomedicines. 10:. PubMed
  257. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
  258. Kapralov AA, et al. 2020. Nat Chem Biol. 278:16. PubMed
  259. Zheng H, et al. 2021. Frontiers in Immunology. 12:645100. PubMed
  260. Han J, et al. 2015. Cancer Res . 75: 5273 - 5282. PubMed
  261. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  262. Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
  263. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  264. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  265. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  266. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
RRID
AB_893232 (BioLegend Cat. No. 101227)
AB_893232 (BioLegend Cat. No. 101228)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Go To Top Version: 2    Revision Date: 11.19.2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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