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- Clone
- VIM15b (See other available formats)
- Regulatory Status
- RUO
- Workshop
- HCDM listed
- Other Names
- CD92, CDw92, CTL1, SLC44A1
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood monocytes were stained with CD92 (clone VIM15b) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 371403 | 25 tests | 123€ | ||||
| 371404 | 100 tests | 268€ | ||||
CD92, also known as CDW92 and CTL1, is a 70kD choline transporter-like transmembrane protein. CD92 is important for transport of choline across the membrane for synthesis of cell membrane components and the neurotransmitter, acetylcholine. CD92 is primarily expressed on monocytes and neutrophils, but can also be found on other myeloid and T-cell subsets. Ionomycin or calcium ionophore mediates the maturation of monocytic dendritic cells causing down-regulation of CD92 but treatment with IL-10 causes re-expression.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- MV4-11
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
-
Application References
(PubMed link indicates BioLegend citation) -
- Wille S, et al. 2001. J. Immunol. 167:5795.
- RRID
-
AB_2616926 (BioLegend Cat. No. 371403)
AB_2616926 (BioLegend Cat. No. 371404)
Antigen Details
- Structure
- 70kD choline transporter-like transmembrane protein.
- Distribution
-
Monocytes, neutrophils, and certain groups of T-cells.
- Function
- Transport of choline through the cell membrane.
- Interaction
- Choline.
- Cell Type
- Monocytes, Neutrophils, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Schenkel LC, et al. 2015. FASEB J. 29:1663.
2. Yamada T, et al. 2011. Neurochem. Int. 58:354.
3. Fullerton MD, et al. 2006. Am. J. Physiol. Cell Physiol. 290:C1230. - Gene ID
- 23466 View all products for this Gene ID
- UniProt
- View information about CD92 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD92 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD92 | VIM15b | FC |
| PE anti-human CD92 | VIM15b | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD92
Human peripheral blood monocytes were stained with purified ... -
PE anti-human CD92
Human peripheral blood monocytes were stained with CD92 (clo...
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