- Clone
- BJ40 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Blast-1, SLAMF2, HuLy-m3
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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336717 | 25 tests | 147€ | ||||
336718 | 100 tests | 329€ |
CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
Additional reported applications (for the relevant formats) include: immunoprecipitation.
-
Application References
(PubMed link indicates BioLegend citation) -
- Kishimoto T, et al. 1997. Leucocyte Typing VI:White Cell Differentiation Antigens. Garland Publishing Inc.
- Wang R, et al. 2012. J. Leukoc Biol. 91:299. PubMed
- RRID
-
AB_2814231 (BioLegend Cat. No. 336717)
AB_2814231 (BioLegend Cat. No. 336718)
Antigen Details
- Structure
- CD2 family, contains 2 IgSF domains, GPI-membrane anchored, 40-47 kD
- Distribution
-
Widely expressed on hematopoietic cells except granulocytes, platelets, and erythrocytes. Increased on T and B cells after activation
- Function
- Contributes to T cell antigen recognition
- Ligand/Receptor
- CD2
- Cell Targets
- Lck, Fyn interact with cytoplasmic domain
- Cell Type
- B cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Fisher RC and Thorley-Lawson DA. 1991. Mol. Cell. Biol. 11:1614.
- Korinek V, et al. 1991. Immunogenetics 33:108.
- Leukocyte Typing IV. Knapp W, et al. (Eds) Oxford University Press (1989)
- Leukocyte Typing V. Schlossman S, et al. (Eds) Oxford University Press (1995)
- Gene ID
- 962 View all products for this Gene ID
- UniProt
- View information about CD48 on UniProt.org
Related FAQs
Other Formats
View All CD48 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD48 | BJ40 | FC,IP |
FITC anti-human CD48 | BJ40 | FC |
PE anti-human CD48 | BJ40 | FC |
TotalSeq™-A0029 anti-human CD48 | BJ40 | PG |
TotalSeq™-C0029 anti-human CD48 | BJ40 | PG |
PerCP/Cyanine5.5 anti-human CD48 | BJ40 | FC |
APC anti-human CD48 | BJ40 | FC |
PE/Cyanine7 anti-human CD48 | BJ40 | FC |
TotalSeq™-B0029 anti-human CD48 | BJ40 | PG |
TotalSeq™-D0029 anti-human CD48 | BJ40 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD48
Human peripheral blood lymphocytes stained with purified BJ4... -
FITC anti-human CD48
Human peripheral blood lymphocytes stained with BJ40 FITC -
PE anti-human CD48
Human peripheral blood lymphocytes stained with BJ40 PE -
TotalSeq™-A0029 anti-human CD48
-
TotalSeq™-C0029 anti-human CD48
-
PerCP/Cyanine5.5 anti-human CD48
Human peripheral blood lymphocytes were stained with CD48 (c... -
APC anti-human CD48
Human peripheral blood lymphocytes were stained with CD48 (c... -
PE/Cyanine7 anti-human CD48
Human peripheral blood lymphocytes were stained with CD48 (c... -
TotalSeq™-B0029 anti-human CD48
-
TotalSeq™-D0029 anti-human CD48
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