- Clone
- HI149 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- V CD01.01
- Other Names
- T6, R4
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Human T lymphoblastic leukemia cell line Molt-4 stained with biotinylated HI149, followed by Sav-PE
Cat # | Size | Price | Quantity Check Availability | Save | ||
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300112 | 100 µg | £129 |
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
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Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections.
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Application References
(PubMed link indicates BioLegend citation) - Product Citations
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- RRID
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AB_389344 (BioLegend Cat. No. 300112)
Antigen Details
- Structure
- Ig superfamily, MHC I-like molecule, type I transmembrane glycoprotein, 49 kD
- Distribution
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Cortical thymocytes, Langerhans cells, dendritic cells
- Function
- Antigen presentation, lymphocyte activation, thymic T cell development
- Ligand/Receptor
- CD1-restricted TCRs
- Cell Type
- Dendritic cells, Langerhans cells, Thymocytes
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
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- Blumberg RS, et al. 1995. Immunol. Rev. 147:5.
- Calabi F, et al. 1991. Tissue Antigens 37:1.
- Melian A, et al. 1996. Curr. Opin. Immunol. 8:82.
- Gene ID
- 909 View all products for this Gene ID
- UniProt
- View information about CD1a on UniProt.org
Related FAQs
- How many biotin molecules are per antibody structure?
- We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Other Formats
View All CD1a Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
FITC anti-human CD1a | HI149 | FC |
PE anti-human CD1a | HI149 | FC |
PE/Cyanine5 anti-human CD1a | HI149 | FC |
APC anti-human CD1a | HI149 | FC |
Purified anti-human CD1a | HI149 | FC,IHC-F |
Biotin anti-human CD1a | HI149 | FC |
Alexa Fluor® 488 anti-human CD1a | HI149 | FC |
Alexa Fluor® 647 anti-human CD1a | HI149 | FC |
Pacific Blue™ anti-human CD1a | HI149 | FC |
Alexa Fluor® 700 anti-human CD1a | HI149 | FC |
Brilliant Violet 421™ anti-human CD1a | HI149 | FC |
PE/Cyanine7 anti-human CD1a | HI149 | FC |
APC/Cyanine7 anti-human CD1a | HI149 | FC |
PerCP/Cyanine5.5 anti-human CD1a | HI149 | FC |
PE/Dazzle™ 594 anti-human CD1a | HI149 | FC |
TotalSeq™-A0402 anti-human CD1a | HI149 | PG |
TotalSeq™-C0402 anti-human CD1a | HI149 | PG |
Brilliant Violet 711™ anti-human CD1a | HI149 | FC |
APC/Fire™ 750 anti-human CD1a | HI149 | FC |
Brilliant Violet 605™ anti-human CD1a | HI149 | FC |
TotalSeq™-B0402 anti-human CD1a | HI149 | PG |
TotalSeq™-D0402 anti-human CD1a | HI149 | PG |
Brilliant Violet 510™ anti-human CD1a | HI149 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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FITC anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
PE anti-human CD1a
Molt-4 (T leukemia cell line) stained with HI149 PE -
PE/Cyanine5 anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
APC anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
Purified anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
Biotin anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
Alexa Fluor® 488 anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
Alexa Fluor® 647 anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
Pacific Blue™ anti-human CD1a
Human T leukemia cell line, Molt-4, stained with HI149 Pacif... -
Alexa Fluor® 700 anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
Brilliant Violet 421™ anti-human CD1a
Human T leukemia cell line (MOLT-4) was stained with CD1a (c... -
PE/Cyanine7 anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with... -
APC/Cyanine7 anti-human CD1a
Human T-lymphoblastic leukemia cell line Molt-4 were stained... -
PerCP/Cyanine5.5 anti-human CD1a
Human T leukemia cell line (MOLT-4) was stained with CD1a (c... -
PE/Dazzle™ 594 anti-human CD1a
Human T leukemia cell line (MOLT-4) was stained with CD1a (c... -
TotalSeq™-A0402 anti-human CD1a
-
TotalSeq™-C0402 anti-human CD1a
-
Brilliant Violet 711™ anti-human CD1a
Human T leukemia cell line (MOLT-4) was stained with CD1a (c... -
APC/Fire™ 750 anti-human CD1a
Human T leukemia cell line (MOLT-4) was stained with CD1a (c... -
Brilliant Violet 605™ anti-human CD1a
Human T leukemia cell line (MOLT-4) was stained with CD1a (c... -
TotalSeq™-B0402 anti-human CD1a
-
TotalSeq™-D0402 anti-human CD1a
-
Brilliant Violet 510™ anti-human CD1a
Human T lymphoblastic leukemia cell line (MOLT-4) was staine...
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