- Clone
- W18070C (See other available formats)
- Regulatory Status
- RUO
- Other Names
- NKR-P1A
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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307503 | 25 tests | £89 | ||||
307504 | 100 tests | £200 |
CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Human CD161 transfected cell line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2876602 (BioLegend Cat. No. 307503)
AB_2876602 (BioLegend Cat. No. 307504)
Antigen Details
- Structure
- Type II glycoprotein, 40-44 kD homodimer, C-type lectin superfamily
- Distribution
-
NK cells, T subset, subset of CD3+ thymocytes
- Ligand/Receptor
- LLT-1 (Lectin-like transcript-1)
- Cell Type
- NK cells, T cells, Thymocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
-
- Takahashi T, et al. 2006. J Immunol. 176:211-6.
- Cosmi L, et al. 2008. J Exp Med. 205:1903-16.
- Aldemir H, et al. 2005. J Immunol. 175:7791-5.
- Rosen DB, et al. 2008. J Immunol. 180:6508-17.
- Gene ID
- 3820 View all products for this Gene ID
- UniProt
- View information about CD161 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD161 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD161 | W18070C | FC |
Purified anti-human CD161 | W18070C | FC |
Alexa Fluor® 647 anti-human CD161 | W18070C | FC |
PE/Cyanine7 anti-human CD161 | W18070C | FC |
PE/Dazzle™ 594 anti-human CD161 | W18070C | FC |
APC/Fire™ 750 anti-human CD161 | W18070C | FC |
APC anti-human CD161 | W18070C | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
PE anti-human CD161
Human peripheral blood lymphocytes stained with CD4 APC and ... -
Purified anti-human CD161
Human peripheral blood lymphocytes were stained with purifie... -
Alexa Fluor® 647 anti-human CD161
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Cyanine7 anti-human CD161
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Dazzle™ 594 anti-human CD161
Human peripheral blood lymphocytes were stained with anti-hu... -
APC/Fire™ 750 anti-human CD161
Human peripheral blood lymphocytes was stained with anti-hum... -
APC anti-human CD161
Human peripheral blood lymphocytes were stained with anti-hu...
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