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PE anti-human CD71 Antibody

Pricing & Availability
Clone
CY1G4 (See other available formats)
Regulatory Status
RUO
Workshop
A015
Other Names
T9, Transferrin receptor
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
CY1G4_PE_021009.jpg
PHA-stimulated (3 days) human peripheral blood lymphocytes stained with CY1G4 PE
  • CY1G4_PE_021009.jpg
    PHA-stimulated (3 days) human peripheral blood lymphocytes stained with CY1G4 PE
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334105 25 tests £84
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334106 100 tests £184
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Description

CD71 is a 95 kD type II homodimeric transmembrane glycoprotein also known as T9 and transferrin receptor. It is expressed on proliferating cells, reticulocytes, and erythroid precursors. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
NALM-6 pre-B cell line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Perik-Zavodskii R, et al. 2022. Genes (Basel). 13: . PubMed
  2. Segal JM, et al. 2019. Nat Commun. 10:3350. PubMed
  3. Angiari S, et al. 2020. Cell Metab. 31:391. PubMed
  4. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  5. Pérez-Quintero L, et al. 2014. J Exp Med. 211:727. PubMed
  6. Turner JS, et al. 2021. Nature. 596:109. PubMed
  7. Himadewi P, et al. 2021. Elife. 10:. PubMed
  8. Liu S, et al. 2021. Mol Ther. 29:1918. PubMed
  9. Morrison TA, et al. 2018. Blood Cells Mol Dis. 69:1. PubMed
  10. Kanemasa H, et al. 2021. Sci Rep. 11:14396. PubMed
  11. Davis CW et al. 2019. Cell. 177(6):1566-1582 . PubMed
  12. Ochi K, et al. 2014. Stem Cells Trans Med. 3:792. PubMed
  13. Turner JS, et al. 2020. Nature. 586:127. PubMed
  14. Lai Y, et al. 2022. Clin Transl Med. 12:e999. PubMed
  15. Yang W, et al. 2015. PLoS One. 10: 0134995. PubMed
  16. Mndez-Mancilla A, et al. 2021. Cell Chemical Biology. 29:321. PubMed
  17. Hollevoet K, et al. 2014. Mol Cancer Ther. 13:2040. PubMed
  18. Hollevoet K, et al. 2015. PLoS One. 10:122462. PubMed
  19. Asada S, et al. 2018. Nat Commun. 9:2733. PubMed
  20. Turner JS, et al. 2021. Nature. 595:421. PubMed
  21. Kwok I, et al. 2020. Immunity. 53(2):303-318.e5. PubMed
  22. Dyson MR, et al. 2020. MAbs. 12:1829335. PubMed
  23. Hill DL, et al. 2019. J Exp Med. 216:1857. PubMed
  24. Perik-Zavodskii R, et al. 2022. Genes (Basel). 13:. PubMed
RRID
AB_2271603 (BioLegend Cat. No. 334105)
AB_2271603 (BioLegend Cat. No. 334106)

Antigen Details

Structure
Transferrin receptor family, type II glycoprotein, 95 kD
Distribution

Proliferating cells, reticulocytes, erythroid precursors

Function
Mediates uptake of iron
Ligand/Receptor
Transferrin
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Hentze M, et al. 1996. P. Natl. Acad. Sci. USA 93:8175.
2. Trowbridge I, et al. 1993. Annu. Rev. Cell Biol. 9:129.

Gene ID
7037 View all products for this Gene ID
UniProt
View information about CD71 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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