- Clone
- NK92.39 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Tactile (T cell-activated increased late expression)
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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338421 | 100 µg | £136 | ||||
338422 | 1 mg | £486 |
Select size of product is eligible for a 40% discount! Promotion valid until December 31, 2024. Exclusions apply. To view full promotion terms and conditions or to contact your local BioLegend representative to receive a quote, visit our webpage.
CD96, known as TACTILE (T cell-activated increased late expression), is a 160 kD type I transmembrane glycoprotein and is a member of the Ig superfamily molecules. It is expressed on NK cells, T cells (up-regulated upon activation), and some acute myeloid leukemia (AML) cells, but not on normal B and myeloid cells. A soluble form of CD96 has been found in serum. CD96 is involved in T- and NK-cell adhesion through interaction with its ligand, CD155 (polio virus receptor).
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- 0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
- Endotoxin Level
- Less than 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
FA - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional reported applications include: block interaction of CD96 with PVR and functional assay
-
Application References
(PubMed link indicates BioLegend citation) -
- Fuchs A, et al. 2004. J. Immunol. 172:3994
- Manes TD, et al. 2011. J. Immunol. 186:1763. PubMed
- RRID
-
AB_2810529 (BioLegend Cat. No. 338421)
AB_2810529 (BioLegend Cat. No. 338422)
Antigen Details
- Structure
- 160 kD, type I transmembrane protein, Ig superfamily
- Distribution
-
NK cells, T cells (upregulated upon activation)
- Ligand/Receptor
- CD155 (PVR)
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity, Inhibitory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Hosen N, et al. 2007. Proc. Natl. Acad. Sci. USA 104:11008
3. Gong J, et al. 2008. Clin. Exp. Immunol. - Gene ID
- 10225 View all products for this Gene ID
- UniProt
- View information about CD96 on UniProt.org
Related FAQs
- Do you guarantee that your antibodies are totally pathogen free?
-
BioLegend does not test for pathogens in-house aside from the GoInVivo™ product line. However, upon request, this can be tested on a custom basis with an outside, independent laboratory.
- Does BioLegend test each Ultra-LEAF™ antibody by functional assay?
-
No, BioLegend does not test Ultra-LEAF™ antibodies by functional assays unless otherwise indicated. Due to the possible complexities and variations of uses of biofunctional antibodies in different assays and because of the large product portfolio, BioLegend does not currently perform functional assays as a routine QC for the antibodies. However, we do provide references in which the antibodies were used for functional assays and we do perform QC to verify the specificity and quality of the antibody based on our strict specification criteria.
- Does BioLegend test each Ultra-LEAF™ antibody for potential pathogens?
-
No, BioLegend does not test for pathogens in-house unless otherwise indicated. However, we can recommend an outside vendor to perform this testing as needed.
- Have you tested this Ultra-LEAF™ antibody for in vivo or in vitro applications?
-
We don't test our antibodies for in vivo or in vitro applications unless otherwise indicated. Depending on the product, the TDS may describe literature supporting usage of a particular product for bioassay. It may be best to further consult the literature to find clone specific information.
Other Formats
View All CD96 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD96 (TACTILE) | NK92.39 | FC,FA |
PE anti-human CD96 (TACTILE) | NK92.39 | FC |
APC anti-human CD96 (TACTILE) | NK92.39 | FC |
PerCP/Cyanine5.5 anti-human CD96 (TACTILE) | NK92.39 | FC |
PE/Dazzle™ 594 anti-human CD96 (TACTILE) | NK92.39 | FC |
Brilliant Violet 421™ anti-human CD96 (TACTILE) | NK92.39 | FC |
PE/Cyanine7 anti-human CD96 (TACTILE) | NK92.39 | FC |
TotalSeq™-A0175 anti-human CD96 (TACTILE) | NK92.39 | PG |
TotalSeq™-C0175 anti-human CD96 (TACTILE) | NK92.39 | PG |
Ultra-LEAF™ Purified anti-human CD96 (TACTILE) | NK92.39 | FC,FA |
TotalSeq™-B0175 anti-human CD96 (TACTILE) | NK92.39 | PG |
TotalSeq™-D0175 anti-human CD96 (TACTILE) | NK92.39 | PG |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD96 (TACTILE)
-
PE anti-human CD96 (TACTILE)
-
APC anti-human CD96 (TACTILE)
-
PerCP/Cyanine5.5 anti-human CD96 (TACTILE)
-
PE/Dazzle™ 594 anti-human CD96 (TACTILE)
-
Brilliant Violet 421™ anti-human CD96 (TACTILE)
-
PE/Cyanine7 anti-human CD96 (TACTILE)
-
TotalSeq™-A0175 anti-human CD96 (TACTILE)
-
TotalSeq™-C0175 anti-human CD96 (TACTILE)
-
Ultra-LEAF™ Purified anti-human CD96 (TACTILE)
-
TotalSeq™-B0175 anti-human CD96 (TACTILE)
-
TotalSeq™-D0175 anti-human CD96 (TACTILE)
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