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PE anti-human CD26 Antibody

Pricing & Availability
Clone
BA5b (See other available formats)
Regulatory Status
RUO
Workshop
VI N-L078
Other Names
ADA-binding protein, DPP IV ectoenzyme, EC 3.4.14.5
Isotype
Mouse IgG2a, κ
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Product Citations
publications
BA5b_PE_062107
Human peripheral blood lymphocytes stained with BA5b PE
  • BA5b_PE_062107
    Human peripheral blood lymphocytes stained with BA5b PE
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
302705 25 tests £76
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302706 100 tests £167
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Description

CD26 is a 110 kD type II membrane protein also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV). It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45 and ADA.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Press. London.
  2. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Cadosch D, et al. 2010. Injury. 41:4. PubMed
  2. Seo HR, et al. 2022. Int J Mol Sci. 23: . PubMed
  3. Dong G 2023. Cell Metabolism. N/A. PubMed
  4. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  5. Haugstøyl ME, et al. 2023. Front Immunol. 14:1130370. PubMed
  6. Hu Y, et al. 2023. Front Immunol. 14:1128423. PubMed
  7. Demchenko A, et al. 2023. Int J Mol Sci. 24:. PubMed
  8. Jacob A, et al. 2020. Nature Protocols. 14(12):3303-3332.. PubMed
  9. Scheuplein V, et al. 2015. J Virol. 89:3859. PubMed
  10. Alysandratos KD, et al. 2021. Cell Reports. 36(9):109636. PubMed
  11. Kohli A, et al. 2022. Life Sci Alliance. 5:. PubMed
  12. Arda HE et al. 2018. Cell systems. 7(3):310-322 . PubMed
  13. Berical A, et al. 2022. Nat Commun. 13:4270. PubMed
  14. McCauley KB, et al. 2018. Curr Protoc Stem Cell Biol. 45:e51. PubMed
  15. Hirai H, et al. 2022. Mol Ther Methods Clin Dev. 24:11. PubMed
  16. Worthen CA, et al. 2020. J Invest Dermatol. 140:2515. PubMed
  17. Suzuki S, et al. 2021. STAR Protocols. 2:100683. PubMed
  18. Huang J, et al. 2020. Cell Stem Cell. 27(6):962-973.e7. PubMed
  19. Wang S, et al. 2010. Nephrol Dial Transplant. 26:2144. PubMed
  20. Spitalieri P, et al. 2022. Cells. 11:. PubMed
  21. Mithal A, et al. 2020. Nat Commun. 0.607638889. PubMed
  22. Hawkins FJ, et al. 2020. Cell Stem Cell. 28(1):79-95.e8. PubMed
  23. O'Connor MH, et al. 2021. Commun Biol. 4:563. PubMed
  24. Yoon YJ, et al. 2022. Nat Commun. 13:3291. PubMed
  25. Jacob A, et al. 2017. Cell Stem Cell. 1.202777778. PubMed
RRID
AB_314289 (BioLegend Cat. No. 302705)
AB_314289 (BioLegend Cat. No. 302706)

Antigen Details

Structure
Peptidases and ectoenzyme families, type II glycoprotein, 110 kD
Distribution

Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages

Function
Dipeptidyl peptidase, T cell costimulation, HIV entry
Ligand/Receptor
Adenosine-deaminase, collagen
Cell Type
B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Kameoka J, et al. 1993. Science 261:466.
2. Dang N, et al. 1990. J. Exp. Med. 172:649.

Gene ID
1803 View all products for this Gene ID
UniProt
View information about CD26 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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