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Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
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Product Citations
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93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
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101301 50 µg £25
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101302 500 µg £79
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Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References

(PubMed link indicates BioLegend citation)
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  2. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  3. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  4. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  5. Ding P, et al. 2022. Elife. 11:. PubMed
  6. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  7. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  8. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  9. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  10. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  11. Li L, et al. 2023. iScience. 26:106095. PubMed
  12. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  13. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  14. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  15. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  16. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  17. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  18. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  19. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  20. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  21. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  22. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  23. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  24. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  25. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  26. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  27. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  28. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  29. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  30. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  31. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  32. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  33. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  34. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  35. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  36. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  37. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  38. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  39. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  40. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  41. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  42. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  43. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  44. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  45. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  46. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  47. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  48. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  49. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  50. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  51. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  52. Miyao T, et al. 2022. Elife. 11: . PubMed
  53. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  54. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  55. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  56. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  57. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  58. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  59. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  60. Akalu YT, et al. 2022. Elife. 11: . PubMed
  61. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  62. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  63. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  64. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  65. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  66. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  67. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  68. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  69. Cousin N, et al. 2022. Cells. 12: . PubMed
  70. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  71. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  72. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  73. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  74. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  75. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  76. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  77. Liu X, et al. 2022. Pain. 163:508. PubMed
  78. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  79. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  80. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  81. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  82. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  83. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  84. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  85. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  86. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  87. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  88. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  89. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  90. Barkaway A, et al. 2021. Immunity. . PubMed
  91. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  92. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  93. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  94. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  95. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  96. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  97. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  98. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  99. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  100. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  101. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  102. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  103. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  104. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  105. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  106. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  107. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  108. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  109. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  110. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  111. Mevel R, et al. 2020. eLife. 9:00. PubMed
  112. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  113. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  114. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  115. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  116. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  117. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  118. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  119. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  120. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  121. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  122. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  123. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  124. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  125. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  126. Feng J, et al. 2021. iScience. 24:103004. PubMed
  127. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  128. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  129. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  130. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  131. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  132. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  133. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  134. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  135. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  136. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  137. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  138. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  139. Goel S, et al. 2017. Nature. 548:471. PubMed
  140. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  141. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  142. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  143. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  144. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  145. Diao L, et al. 2022. iScience. 25:105511. PubMed
  146. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  147. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  148. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  149. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  150. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  151. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  152. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  153. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  154. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  155. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  156. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  157. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  158. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  159. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  160. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  161. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  162. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  163. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  164. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  165. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  166. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  167. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  168. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  169. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  170. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  171. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  172. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  173. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  174. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  175. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  176. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  177. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  178. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  179. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  180. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  181. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  182. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  183. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  184. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  185. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  186. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  187. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  188. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  189. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  190. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  191. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  192. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  193. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  194. Tal MC, et al. 2020. MBio. 11:00. PubMed
  195. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  196. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  197. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  198. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  199. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  200. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  201. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  202. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  203. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  204. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  205. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  206. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  207. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  208. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  209. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  210. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  211. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  212. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  213. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  214. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  215. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  216. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  217. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  218. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  219. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  220. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  221. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  222. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  223. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  224. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  225. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  226. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  227. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  228. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  229. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  230. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  231. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  232. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  233. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  234. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  235. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  236. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  237. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  238. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  239. Wong HS, et al. 2021. Cell. . PubMed
  240. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  241. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  242. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  243. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  244. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  245. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  246. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  247. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  248. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  249. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  250. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  251. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  252. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  253. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  254. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  255. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  256. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  257. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  258. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  259. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  260. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  261. Baasch S, et al. 2021. Cell. . PubMed
  262. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  263. Zheng J, et al. 2020. bioRxiv. . PubMed
  264. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  265. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  266. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  267. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  268. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  269. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  270. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  271. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  272. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  273. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  274. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  275. Welte T, et al. 2021. iScience. 24:103349. PubMed
  276. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  277. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  278. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  279. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  280. Xu S, et al. 2021. Immunity. . PubMed
  281. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  282. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  283. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  284. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  285. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  286. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  287. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  288. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  289. Roy K, et al. 2019. Immunity. 50:616. PubMed
  290. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  291. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  292. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  293. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  294. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  295. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  296. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  297. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  298. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  299. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  300. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  301. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  302. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  303. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  304. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  305. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  306. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  307. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  308. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  309. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  310. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  311. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  312. Zheng J, et al. 2020. Nature. . PubMed
  313. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  314. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  315. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  316. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  317. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  318. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  319. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  320. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  321. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  322. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  323. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  324. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  325. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  326. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  327. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  328. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  329. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  330. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  331. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  332. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  333. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  334. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  335. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  336. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  337. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  338. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  339. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  340. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  341. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  342. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  343. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  344. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  345. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  346. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  347. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  348. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  349. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  350. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  351. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  352. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  353. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  354. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  355. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  356. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  357. Lenert R 2005. J Immunol. 174:2429. PubMed
  358. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  359. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  360. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  361. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  362. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  363. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  364. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  365. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  366. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  367. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  368. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  369. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  370. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  371. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  372. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  373. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  374. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  375. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  376. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  377. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  378. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  379. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  380. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  381. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  382. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  383. Lee SA, et al. 2021. Cells. 10:. PubMed
  384. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  385. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  386. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  387. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  388. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  389. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  390. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  391. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  392. William M, et al. 2018. J Immunol. 200:4102. PubMed
  393. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  394. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  395. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  396. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  397. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  398. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  399. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  400. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  401. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  402. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  403. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  404. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  405. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  406. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  407. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  408. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  409. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  410. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  411. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  412. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  413. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  414. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  415. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  416. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  417. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  418. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  419. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  420. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  421. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  422. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  423. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  424. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  425. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  426. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  427. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  428. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  429. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  430. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  431. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  432. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  433. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  434. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  435. Sibler E, et al. 2021. Cells. 10:. PubMed
  436. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  437. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  438. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  439. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  440. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  441. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  442. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  443. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  444. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  445. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  446. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  447. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  448. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  449. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  450. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  451. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  452. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  453. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  454. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  455. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  456. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  457. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312800 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 01/23/2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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