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PE/Cyanine7 anti-mouse CD11c Antibody

Pricing & Availability
Clone
N418 (See other available formats)
Regulatory Status
RUO
Other Names
αX integrin, integrin αX chain, CR4, p150, ITGAX
Isotype
Armenian Hamster IgG
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Product Citations
publications
N418_PECyanine7_CD11c_Antibody_1_111924
C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (left) or PE/Cyanine7 Armenian hamster IgG isotype control (right)
  • N418_PECyanine7_CD11c_Antibody_1_111924
    C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (left) or PE/Cyanine7 Armenian hamster IgG isotype control (right)
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
117317 25 µg £65
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117318 100 µg £159
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Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for other applications.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Additional Product Notes

View more applications data for this product in our Scientific Poster Library.

Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  2. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  3. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  4. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  5. Friess MC, et al. 2022. Cell Rep. 38:110334. PubMed
  6. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  7. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  8. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  9. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  10. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  11. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  12. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  13. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  14. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  15. Mirchandani AS, et al. 2022. Nat Immunol. 23:927. PubMed
  16. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  17. He Y, et al. 2022. Front Immunol. 13:986202. PubMed
  18. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  19. Hill AA, et al. 2023. JCI Insight. 8: . PubMed
  20. Tatsumi N, et al. 2022. STAR Protoc. 3:101845. PubMed
  21. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  22. Cousin N, et al. 2022. Cells. 12: . PubMed
  23. Sieow JL, et al. 2023. Int J Mol Sci. 24: . PubMed
  24. Lombard-Vadnais F, et al. 2023. iScience. 26:105852. PubMed
  25. Gonçalves R, et al. 2023. iScience. 26:105972. PubMed
  26. Wei J, et al. 2022. Cancer Prev Res (Phila). 15:285. PubMed
  27. Hailemichael Y, et al. 2022. Cancer Cell. 40:509. PubMed
  28. Morris CR, et al. 2022. Mucosal Immunol. 15:977. PubMed
  29. Kedmi R, et al. 2022. Nature. 610:737. PubMed
  30. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  31. Lutz MB, et al. 2022. Eur J Immunol. . PubMed
  32. Jia DJ, et al. 2022. Gut Microbes. 14:2145843. PubMed
  33. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  34. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  35. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  36. Xu H, et al. 2023. Elife. 12:. PubMed
  37. Matsuzawa M, et al. 2023. Nat Commun. 14:1417. PubMed
  38. Palakurthi B, et al. 2023. Nat Commun. 14:2109. PubMed
  39. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  40. He Y, et al. 2023. Biomolecules. 13:. PubMed
  41. Zeng S, et al. 2023. Front Oncol. 13:1171926. PubMed
  42. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  43. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  44. Kimura S, et al. 2020. Nat Commun. 0.620833333. PubMed
  45. Al–Rashed F, et al. 2020. Sci Rep. 10:16802. PubMed
  46. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  47. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  48. Kolawole A, et al. 2015. J Virol. 90: 1499-1506. PubMed
  49. Kawano H, et al. 2016. Int Immunol. 28: 489 - 501. PubMed
  50. Shin J, et al. 2016. Sci Rep. 6:23426. PubMed
  51. van Vloten JP, et al. 2022. J Immunother Cancer. 10:. PubMed
  52. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  53. Jong RM, et al. 2022. J Immunol. 208:407. PubMed
  54. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  55. Fu R, et al. 2020. Sci Rep. 10:1455. PubMed
  56. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  57. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  58. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  59. Suzuki T, et al. 2014. J Dermatol Sci. 74:116. PubMed
  60. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  61. Ndoja A, et al. 2020. Cell. 182(5):1156-1169.e12. PubMed
  62. Dong L, et al. 2021. Cancer Cell. . PubMed
  63. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  64. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  65. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  66. Boldison J, et al. 2020. Cell Mol Immunol. 17:843. PubMed
  67. Liang S, et al. 2022. Acta Pharm Sin B. 12:2494. PubMed
  68. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  69. Thwe PM et al. 2017. Cell metabolism. 26(3):558-567 . PubMed
  70. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  71. Quatrini L, et al. 2018. Nat Immunol. 19:954. PubMed
  72. Pack AD, et al. 2021. Cell Reports. 36:109586. PubMed
  73. Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
  74. Yousif AS, et al. 2020. Immunity. 54(2):235-246.e5. PubMed
  75. Ku M, et al. 2016. Mol Cancer Ther. 15: 1975 - 1987. PubMed
  76. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  77. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  78. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  79. Yu X, et al. 2021. Nature. 594:560. PubMed
  80. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  81. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  82. Morgado P, et al. 2014. Infect Immun . 82:4047. PubMed
  83. Ohtsuki T, et al. 2016. J Virol. 90: 300 - 307. PubMed
  84. Bazett M, Haston M 2016. Sci Rep. 6:19189. PubMed
  85. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  86. Si Y, et al. 2020. Sci Adv. 6:eaba0995. PubMed
  87. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  88. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  89. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  90. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  91. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  92. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  93. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  94. Moreau GB, et al. 2020. Am J Trop Med Hyg. 103:1215. PubMed
  95. Khan IM, et al. 2021. Immunohorizons. 5:703. PubMed
  96. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  97. Zhang C, et al. 2021. Clin Transl Immunology. 10:e1310. PubMed
  98. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  99. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  100. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  101. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  102. van Dierendonck XAMH, et al. 2020. Cell Reports. 30(6):1811-1822. PubMed
  103. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  104. Britton GJ et al. 2019. Immunity. 50(1):212-224 . PubMed
  105. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  106. Škrnjug I, et al. 2014. PLoS One. 9:110150. PubMed
  107. Lee M, et al. 2014. PLoS One. 9:112666. PubMed
  108. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  109. Zhang Y, et al. 2015. PLoS Pathog. 11: e1005167. PubMed
  110. Ben-Shaanan T, et al. 2016. Nat Med. 10.1038/nm.4133. PubMed
  111. Koren N, et al. 2021. Cell Host Microbe. 29(2):197-209.e5. PubMed
  112. Wu X, et al. 2021. Elife. 10:. PubMed
  113. An J,et al. 2017. Sci Rep.. 10.1038/s41598-017-13629-0. PubMed
  114. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  115. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  116. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  117. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  118. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  119. Crosse EI, et al. 2020. Cell Stem Cell. 27:822. PubMed
  120. Sellau J, et al. 2016. Sci Rep. 6:28058. PubMed
  121. Rosen D, et al. 2016. J Infect Dis. 213: 649 - 658. PubMed
  122. Kelsey E Sivick et al. 2018. Cell reports. 25(11):3074-3085 . PubMed
  123. Fatkhullina AR et al. 2018. Immunity. 49(5):943-957 . PubMed
  124. Novkovic M, et al. 2016. PLoS Biol. 14: 1002515. PubMed
  125. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  126. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  127. Connick K, et al. 2020. J Parasit Dis. 186:44. PubMed
  128. Johnson LA, et al. 2021. Life Sci Alliance. :4. PubMed
  129. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  130. Pan Y, et al. 2022. J Clin Invest. 132:. PubMed
  131. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  132. Si Y, et al. 2018. J Control Release. 282:120. PubMed
  133. Baudoux T, et al. 2018. Sci Rep. 4.0375. PubMed
  134. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  135. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  136. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  137. Vettorazzi S, et al. 2015. Nat Commun. 6: 7796. PubMed
  138. Krollmann C, et al. 2022. STAR Protoc. 3:101309. PubMed
  139. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  140. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  141. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  142. Ercoli G, et al. 2022. Clin Transl Immunology. 11:e1366. PubMed
  143. Lewis EL, et al. 2021. Front Immunol. 12:741518. PubMed
  144. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  145. Christ A, et al. 2018. Cell. 172:162. PubMed
  146. Calcinotto A, et al. 2018. Nat Commun. 9:4832. PubMed
  147. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  148. Gibbins J, et al. 2014. Blood. 124:2953. PubMed
  149. Schaefer K, et al. 2014. PLoS One. 9:114824. PubMed
  150. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  151. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  152. Nikolos F, et al. 2022. Nat Commun. 13:1487. PubMed
  153. Colombo M, et al. 2022. iScience. 25:105042. PubMed
  154. Moon HG et al. 2018. Immunity. 49(2):275-287 . PubMed
  155. Hiebert P et al. 2018. Developmental cell. 46(2):145-161 . PubMed
  156. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  157. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  158. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  159. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  160. Reimer E, et al. 2020. J Cell Sci. 134:00:00. PubMed
  161. Cuenca M, et al. 2016. J Immunol. 196: 726 - 737. PubMed
  162. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  163. Ermert D, et al. 2016. PLoS Pathog. 11: 1005043. PubMed
  164. Puigdelloses M, et al. 2021. J Immunother Cancer. 9:. PubMed
  165. Daneshmandi S, et al. 2021. Elife. 10:. PubMed
  166. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  167. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  168. Yang C, et al. 2019. Nanomedicine (Lond). 14:2423. PubMed
  169. Janela B, et al. 2019. Immunity. 50:1069. PubMed
  170. Colliou N, et al. 2015. Toxins. 7: 3805 - 3817. PubMed
  171. Shepardson K, et al. 2016. MBio. 7: e00506-16. PubMed
  172. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  173. Lan H, et al. 2020. Int Immunol. 559:32. PubMed
  174. Taddio MF, et al. 2021. Mol Imaging Biol. 23:196. PubMed
  175. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  176. Yang X, et al. 2022. Front Immunol. 13:856230. PubMed
  177. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  178. Morikawa M, et al. 2016. PLoS One. 11:e0163607. PubMed
  179. Ghorbani S, et al. 2022. Nat Commun. 13:2445. PubMed
  180. Clement CC, et al. 2021. Immunity. 54:721. PubMed
  181. Kim M, et al. 2018. Immunity. 49:151. PubMed
  182. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  183. Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
  184. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  185. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  186. Zwick M, et al. 2019. Front Immunol. 10:222. PubMed
  187. Chan WY, et al. 2019. Infect Immun. 87:. PubMed
  188. Hennion-Tscheltzoff O, et al. 2013. Blood. 121:4684. PubMed
  189. Škrnjug I, et al. 2014. PLoS One. 9:95728. PubMed
  190. Velázquez F, et al. 2016. J Immunol. 196: 1305 - 1316. PubMed
  191. Ghosh D, et al. 2016. J Immunol. 197: 1788 - 1800. PubMed
  192. Yasuda T, et al. 2016. PLoS One. 11:e0167952. PubMed
  193. Kumari P, et al. 2021. Cell Reports. 35(3):109012. PubMed
  194. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  195. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  196. He S, et al. 2021. Front Pharmacol. 12:743837. PubMed
  197. Wang L, et al. 2021. Sci Adv. 7:eabj4796. PubMed
  198. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  199. Andersen TK, et al. 2019. NPJ Vaccines. 4:9. PubMed
  200. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  201. Urata S, et al. 2018. PLoS Pathog. 14:e1007172. PubMed
  202. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  203. Harb H, et al. 2020. Nat Immunol. 1359:21. PubMed
  204. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  205. Niven J, et al. 2019. Cell Rep. 28:21. PubMed
  206. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  207. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  208. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  209. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  210. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  211. Donlan AN, et al. 2021. JCI Insight. 6: . PubMed
  212. Okreglicka K, et al. 2021. J Exp Med. 218:. PubMed
  213. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  214. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  215. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  216. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  217. Van Nuffel E, et al. 2020. EMBO Rep. 21:e49237. PubMed
  218. Liu SS, et al. 2021. Immunity. :. PubMed
  219. Xu C, et al. 2021. Cell Reports. 35(11):109235. PubMed
  220. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  221. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  222. Wan X, Thomas J, Unanue E 2016. J Exp Med. 213: 967 - 978. PubMed
  223. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  224. Stotesbury C, et al. 2020. Aging Cell. 19:e13170. PubMed
  225. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  226. Ceglia V, et al. 2021. J Immunol. 207:2060. PubMed
  227. Bahmani B, et al. 2021. Nat Commun. 12:1999. PubMed
  228. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  229. Lee HN, et al. 2022. JCI Insight. 7:. PubMed
  230. Verma M, et al. 2021. J Exp Med. 218:. PubMed
  231. Kim J, et al. 2020. Adv Funct Mater. 30:. PubMed
  232. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  233. Jin J, et al. 2020. Cell Reports. 30(12):4124-4136. PubMed
  234. Schuh E, et al. 2017. J Immunol. 198:3081. PubMed
  235. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  236. Stack G, et al. 2015. PLoS Pathog. 11:1004641. PubMed
  237. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
  238. Goc J, et al. 2021. Cell. 184:5015. PubMed
  239. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  240. Hsu HP, et al. 2021. J Biol Chem. 296:100419. PubMed
  241. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  242. Dietschmann A, et al. 2020. Eur J Immunol. 50:1044. PubMed
  243. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  244. Albaghdadi AJH, et al. 2019. Sci Rep. 9:6528. PubMed
  245. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  246. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  247. Saleh R, et al. 2018. J Immunol. 201:2042. PubMed
  248. Doo DW, et al. 2020. Ther Adv Med Oncol. 12:1758835920913798. PubMed
  249. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  250. Trivedi S, et al. 2020. Elife. 9:00. PubMed
  251. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
  252. Fontana C, et al. 2016. J Biol Chem. 291: 7727-7741. PubMed
  253. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  254. Wirasinha RC, et al. 2021. J Exp Med. 218: . PubMed
  255. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  256. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  257. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
  258. Thomson CA, et al. 2018. J Immunol. 201:215. PubMed
  259. Chen S, et al. 2018. Nat Commun. 9:5298. PubMed
RRID
AB_493568 (BioLegend Cat. No. 117317)
AB_493568 (BioLegend Cat. No. 117318)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org

Other Formats

View All CD11c Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD11c N418 FC
Biotin anti-mouse CD11c N418 FC,IHC-F
FITC anti-mouse CD11c N418 FC
PE anti-mouse CD11c N418 FC
Purified anti-mouse CD11c N418 FC,CyTOF®,IP,IHC
Alexa Fluor® 488 anti-mouse CD11c N418 FC
Alexa Fluor® 647 anti-mouse CD11c N418 FC,IHC,ICC,3D IHC
PE/Cyanine5 anti-mouse CD11c N418 FC
PE/Cyanine7 anti-mouse CD11c N418 FC
Brilliant Violet 605™ anti-mouse CD11c N418 FC
Alexa Fluor® 700 anti-mouse CD11c N418 FC
Pacific Blue™ anti-mouse CD11c N418 FC
APC/Cyanine7 anti-mouse CD11c N418 FC
PerCP/Cyanine5.5 anti-mouse CD11c N418 FC
PerCP anti-mouse CD11c N418 FC
Brilliant Violet 421™ anti-mouse CD11c N418 FC,IHC
Brilliant Violet 570™ anti-mouse CD11c N418 FC
Brilliant Violet 785™ anti-mouse CD11c N418 FC
Brilliant Violet 510™ anti-mouse CD11c N418 FC
Brilliant Violet 650™ anti-mouse CD11c N418 FC
Purified anti-mouse CD11c (Maxpar® Ready) N418 FC,CyTOF®
Alexa Fluor® 594 anti-mouse CD11c N418 IHC-F,3D IHC
PE/Dazzle™ 594 anti-mouse CD11c N418 FC
Brilliant Violet 711™ anti-mouse CD11c N418 FC
APC/Fire™ 750 anti-mouse CD11c N418 FC
TotalSeq™-A0106 anti-mouse CD11c N418 PG
Brilliant Violet 750™ anti-mouse CD11c N418 FC
TotalSeq™-B0106 anti-mouse CD11c N418 PG
TotalSeq™-C0106 anti-mouse CD11c N418 PG
KIRAVIA Blue 520™ anti-mouse CD11c N418 FC
Spark Blue™ 550 anti-mouse CD11c N418 FC
Spark NIR™ 685 anti-mouse CD11c N418 FC
Spark UV™ 387 anti-mouse CD11c N418 FC
Spark Red™ 718 anti-mouse CD11c N418 FC
Spark Blue™ 515 anti-mouse CD11c N418 FC
PerCP/Fire™ 806 anti-mouse CD11c N418 FC
Spark PLUS UV395™ anti-mouse CD11c N418 FC
Spark Blue™ 574 anti-mouse CD11c (Flexi-Fluor™) N418 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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