Loading...

PE anti-human FcRL6 Antibody

Pricing & Availability
Clone
7B7/FcRL6 (See other available formats)
Regulatory Status
RUO
Other Names
FcRL6, Fc receptor like 6
Isotype
Mouse IgG1, κ
Ave. Rating
Submit a Review
Product Citations
publications
7B7FcRL6_-PE_-FcRL6_Antibody_012421
Human peripheral blood lymphocytes were stained with anti-human CD56 Brilliant Violet 421™ and anti-human FcRL6 (clone 7B7/FcRL6) PE (left) or mouse IgG1, κ isotype control PE (right).
  • 7B7FcRL6_-PE_-FcRL6_Antibody_012421
    Human peripheral blood lymphocytes were stained with anti-human CD56 Brilliant Violet 421™ and anti-human FcRL6 (clone 7B7/FcRL6) PE (left) or mouse IgG1, κ isotype control PE (right).
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
373905 25 tests $171
Check Availability


Need larger quantities of this item?
Request Bulk Quote
373906 100 tests $360
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

FcRL6, a member of Fc receptor-like family, does not bind Ig. It is expressed on cytotoxic NK and a subset of T cells (primarily CD8+ T cells).  Its expression level correlates with the differentiation state of these cells. This Type I transmembrane glycoprotein consists of three Ig-like domains on its extracellular and a consensus ITIM or non-canonical ITAM-like sequence on its cytoplasmic region. Patients with chronic lymphocytic leukemia show higher abundance of this receptor due to expansion of cytotoxic lymphocyte population.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
BW5147 transduced with HA-tagged FcRL6
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC – Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Schreeder DM, et al. 2008. Eur. J. Immunol. 38:3159. (FC)
RRID
AB_2910426 (BioLegend Cat. No. 373905)
AB_2910426 (BioLegend Cat. No. 373906)

Antigen Details

Structure
Type I transmembrane glycoprotein, Ig gene superfamily
Distribution

NK, T subset

Cell Type
NK cells, T cells
Biology Area
Immunology
Molecular Family
Fc Receptors
Antigen References
  1. Davis RS. 2007. Annu Rev Immunol. 25:525-60.
  2. Wilson TJ, et al. 2007. Blood. 109:3786-93.
  3. Schreeder DM, et al. 2008. 38:3159-66.
Gene ID
343413 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
FcRL6
Specificity Alt (DOES NOT SHOW ON TDS):
FcRL6
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about FcRL6 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 01/24/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login/Register
Remember me
Forgot your password? Reset Password
Request an Account