Analyte Specific Reagent. Analytical and performance characteristics are not established.
- Clone
- 7D4-6
- Other Names
- KDR, Vascular Endothelial Receptor 2 (VEGF-R2, VEGFR2, VEGFR)
- Isotype
- Mouse IgG1, κ
Cat # | Size | Price | Quantity Check Availability | Save | ||
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989402 | 500 µL | $370 |
CD309, also known as VEGF-R2, KDR, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, and VEGF-D splice isoforms. Activation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration.
Product DetailsProduct Details
- Reactivity
- Human
- Formulation
- Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 200 µg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
Suggested for Flow Cytometry
- Disclaimer
-
WARNINGS AND PRECAUTIONS
- Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
- This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
- All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
- Do not use this reagent beyond the expiration date stated on the label.
- Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
- Avoid prolonged exposure of the reagent or stained cells to light.
Antigen Details
- Antigen References
-
- Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication.
- Ferrara N and Gerber HP. 2002. Acta. Haematol. 106:148.
- Murohara T, et al. 1998. Circulation. 97:99.
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD309 (VEGFR2)
HUVEC cells were fixed with 1% paraformaldehyde (PFA) and th... HUVEC human endothelial cells were stained with purified CD3... -
PE anti-human CD309 (VEGFR2)
HUVEC human endothelial cells were stained with CD309 (clone... -
PerCP/Cyanine5.5 anti-human CD309 (VEGFR2)
HUVEC human endothelial cells were stained with CD309 (clone... -
Alexa Fluor® 647 anti-human CD309 (VEGFR2)
HUVEC human endothelial cells were stained with CD309 (clone... -
PE/Cyanine7 anti-human CD309 (VEGFR2)
HUVEC human endothelial cells were stained with CD309 (clone... -
Alexa Fluor® 488 anti-human CD309 (VEGFR2)
HUVEC human endothelial cells were stained with CD309 (clone... -
APC anti-human CD309 (VEGFR2)
HUVEC human endothelial cells were stained with CD309 (clone... -
PE/Dazzle™ 594 anti-human CD309 (VEGFR2)
HUVEC human endothelial cells were stained with CD309 (clone... -
TotalSeq™-A0362 anti-human CD309 (VEGFR2)
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TotalSeq™-C0362 anti-human CD309 (VEGFR2)
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TotalSeq™-B0362 anti-human CD309 (VEGFR2)
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APC anti-human CD309
Typical results from HUVEC human endothelial cells stained e...
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