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APC anti-human TSPAN8 Antibody

Pricing & Availability
Clone
TAL69 (See other available formats)
Regulatory Status
RUO
Other Names
Tetraspanin 8, TM4SF3, Transmembrane 4 superfamily member 3, Tumor-associated antigen CO-029, CO-029, Tetraspanin-8, Tspan-8
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
TAL69_APC_TSPAN8_-Antibody_FC_122220.png
Human colon cancer cell line, HT-29, was stained with anti-human TSPAN8 APC (clone TAL69) (filled histogram) or mouse IgG1, κ APC isotype control (open histogram).
  • TAL69_APC_TSPAN8_-Antibody_FC_122220.png
    Human colon cancer cell line, HT-29, was stained with anti-human TSPAN8 APC (clone TAL69) (filled histogram) or mouse IgG1, κ APC isotype control (open histogram).
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363705 25 tests $166
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363706 100 tests $367
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Description

Tetraspanin 8 (TSPAN8) is a member of the transmembrane IV superfamily.  It is a cell surface protein with four hydrophobic domains. It mediates signal transduction events that regulate cell development, activation, growth, and motility. It is expressed in gastric, colon, rectal, and pancreatic carcinomas.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
AsPC1 (Human)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
RRID
AB_2890793 (BioLegend Cat. No. 363705)
AB_2890793 (BioLegend Cat. No. 363706)

Antigen Details

Structure
26 kD.
Distribution

Gastric, colon, rectal, and pancreatic carcinomas.

Function
Regulates cell development, activation, growth, and motility.
Interaction
Interacts with CD106 and CD49b. Complexes with integrins.
Biology Area
Immunology
Antigen References

1. Szala S, et al. 1990. Proc. Natl. Acad. Sci. USA 87:6833.
2. Rana S, et al. 2011. Int. J. Biochem. Cell Biol. 43:106.
3. Nazarenko I, et al. 2010. Cancer Res. 70:1668.
4. Berthier-Vergnes O, et al. 2011. Br. J. Cancer 104:155.

Gene ID
7103 View all products for this Gene ID
UniProt
View information about TSPAN8 on UniProt.org
Go To Top Version: 1    Revision Date: 12/22/2020

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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