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APC anti-mouse CD160 Antibody

Pricing & Availability
Clone
7H1 (See other available formats)
Regulatory Status
RUO
Other Names
BY55, NK1, NK28
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
7H1_APC_CD160_Antibody_FC_1_111113
C57BL/6 mouse splenocytes were stained with NK1.1 Alexa Fluor® 488 and CD160 (clone 7H1) APC (top) or rat IgG2a, κ APC isotype control (bottom).
  • 7H1_APC_CD160_Antibody_FC_1_111113
    C57BL/6 mouse splenocytes were stained with NK1.1 Alexa Fluor® 488 and CD160 (clone 7H1) APC (top) or rat IgG2a, κ APC isotype control (bottom).
  • 7H1_APC_CD160_Antibody_FC_2_111113
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143011 25 µg $90
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143012 100 µg $232
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Description

CD160, also known as BY55, is a 27 kD glycoprotein and member of the Ig superfamily. It is anchored to the cell membrane through glycosylphosphatidylinositol (GPI) and forms disulfide-linked multimers. A soluble form of CD160 is secreted by activated CD8+ T cells. Expressed by NK, NKT, γ/δ T cells, intestinal intraepithelial T cells and a subset of memory CD8+ T cells, CD160 binds both classical and non-classical MHC class I molecules. It is also a ligand for HVEM. CD160 enhances proliferation of activated CD8+ T cells and triggers cell cytotoxicity in NK cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Soluble His-Tag mouse CD160
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Tsujimura K, et al. 2006. Immunol. Lett. 106:48. (FC)
Product Citations
  1. Lv Z, et al. 2020. Oncoimmunology. 9:1747688. PubMed
RRID
AB_2562698 (BioLegend Cat. No. 143011)
AB_2562698 (BioLegend Cat. No. 143012)

Antigen Details

Structure
Membrane glycoprotein, member of the Ig superfamily, 27 kD, glycosylphosphatidylinositol (GPI)-anchored, forms disulfide-linked multimers on the cell surface
Distribution
NK, NKT, γ/δT cells, intestinal intraepithelial T cells, subset of memory CD8+ T cells
Function
Enhances proliferation of activated CD8+ T cells, triggers cell cytotoxicity in NK cells
Ligand/Receptor
Classical and non-classical MHC-class I molecules, HVEM
Cell Type
NK cells, NKT cells, T cells
Biology Area
Immunology, Innate Immunity, Costimulatory Molecules
Molecular Family
CD Molecules, MHC Antigens, TCRs
Antigen References

1. Shui JW, et al. 2011. J. Leukoc. Biol. 89:517.
2. Del Rio ML, et al. 2010. J. Leukoc. Biol. 87:223.
3. Cai G and Freeman GJ. 2009. Immunol. Rev. 229:244.

Gene ID
54215 View all products for this Gene ID
UniProt
View information about CD160 on UniProt.org
Go To Top Version: 1    Revision Date: 11/13/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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