APC anti-mouse TCR Vδ6.3 Antibody anti-TCRV delta 6.3

Pricing & Availability

Clone: C504.17C (See other available formats)
Regulatory Status: RUO
Other Names: TCRd, TCR-delta
Isotype: Rat IgG2b, κ
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Product Citations: publications

C50417C_APC_TCRVS63_Antibody_041218 — C57BL/6 splenocytes were stained with PE anti-mouse TCR γ/δ (clone GL3); these cells were then stained with APC Anti-Mouse TCR vδ6.3 (clone C504.17C; left) or APC Rat IgG2b, κ Isotype Ctrl (right) followed by FITC anti-mouse CD3ε. Data shown were gated on the CD3ε positive population.

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154805

25 µg

$137

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154806

100 µg

$272

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Description

Lymphocytes expressing γ/δ antigen receptors constitute a minor population in lymphoid tissue, but a major population within epidermal, gastrointestinal, and vaginouterine epithelia. γ/δ T cells are involved in immunological surveillance and regulation in these tissues. The C504.17C antibody reacts with Vδ6.3 T-cell receptor (TCR) bearing T cells.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: TCR γδ positive T Cell Hybridoma
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
Application Notes: If clone GL3 is included in multi-color analysis, it is recommended that the cells should be stained with clone GL3 first prior to be stained with clone C504.17C.
RRID: AB_2728221 (BioLegend Cat. No. 154805)
AB_2728221 (BioLegend Cat. No. 154806)

Antigen Details

Structure: Form heterodimer with TCR gamma chain, associate with CD3 complex.
Distribution: Expressed on Vδ6.3 T-cell receptor (TCR) bearing γ/δ T cells
Function: Involved in immunological surveillance and regulation.
Ligand/Receptor: Antigens presented on MHC or MHC-like molecules
Cell Type: T cells
Biology Area: Adaptive Immunity, Immunology
Molecular Family: TCRs
Antigen References: Raulet DH. 1989. Annu Rev Immunol. 7:175.

Allison JP and Havran WL. 1991. Annu Rev Immunol. 9:679.
Gene ID: 110066 View all products for this Gene ID
UniProt: View information about TCR Vdelta6.3 on UniProt.org

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Other Formats

View All TCR Vδ6.3 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse TCR Vδ6.3	C504.17C	FC
PE anti-mouse TCR Vδ6.3	C504.17C	FC
APC anti-mouse TCR Vδ6.3	C504.17C	FC
FITC anti-mouse TCR Vδ6.3	C504.17C	FC

Certificate of Analysis

Go To Top Version: 0 Revision Date: 04/13/2018

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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