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- Regulatory Status
- RUO
- Other Names
- CFP, Complement Factor P
- Ave. Rating
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- Product Citations
- publications
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 448904 | 5 plates | $347 | ||||
Properdin, known as CFP or complement factor P, is a protein that activates the complement regulatory proteins of the innate immune system. It is a glycoprotein produced by leukocytes and found in plasma. It positively regulates alternative pathway activity by stabilizing C3 and C5 convertases. Properdin’s involvement in complement activity changes the cellular microenvironment, therefore contributing to both the innate and adaptive immune response. This includes production of inflammatory cytokines, immune cell infiltration, antigen presenting cell maturation and tissue damage. As an inflammatory modulator, it can enhance damaging inflammation. Studies have shown its implication in several renal diseases, highlighting its role as a potential urinary biomarker. Its role in inflammatory conditions is multifaceted and as such, there is potential for the development of new disease therapies.
Biolegend’s ELISA MAX™ Deluxe Set Human Properdin ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA), utilizing a monoclonal capture antibody and biotinylated monoclonal antibody specific for human Properdin. This set contains necessary reagents for the accurate quantification of natural and recombinant human Properdin in serum, plasma, urine and other biological fluids. Biolegend’s ELISA MAX™ Deluxe Sets are cost-effective, sensitive, accurate, and robust.
Kit Contents
- Kit Contents
-
- Human Properdin ELISA MAX™ Capture Antibody (200X)
- Human Properdin ELISA MAX™ Detection Antibody (200X)
- Human Properdin Standard
- Avidin-HRP (1,000X)
- Substrate Solution D
- Coating Buffer B (5X)
- Assay Diluent B (5X)
Product Details
- Verified Reactivity
- Human
- Application
-
ELISA
- As a part of BioLegend's efforts to go green, each new lot of the ELISA MAX™ sets will include a summarized version of its manual. Click here for more information.
- Sensitivity
- 7.21 pg/mL
- Standard Range
- 23.44 - 1500 pg/mL
- Materials Not Included
-
- Microwell plates: BioLegend Cat. No. 423501 is recommended
- Wash Buffer: BioLegend Cat. No. 421601 is recommended, or PBS + 0.05% Tween-20
- Stop Solution: BioLegend Cat. No. 423001 is recommended, or acid solution, e.g. 2N H2SO4
- Plate Sealers: BioLegend Cat. No. 423601 is recommended
- PBS (Phosphate-Buffered Saline): 8.0 g NaCl, 1.16 g Na2HPO4, 0.2 g KH2PO4, 0.2 g KCl, add deionized water to 1 L; pH to 7.4, 0.2 μm filtered
- Deionized (DI) water
- A microplate reader capable of measuring absorbance at 450 nm
- Adjustable pipettes to measure volumes ranging from 2 μL to 1 mL
- Wash bottle or automated microplate washer
- Log-Log graph paper or software for data analysis
- Tubes to prepare standard dilutions
- Timer
Antigen Details
- Molecular Family
- Scaffold Proteins
- Gene ID
- NA
- UniProt
- View information about Properdin on UniProt.org
Related FAQs
- Do the ELISA MAX™ Deluxe Sets come with plates?
-
No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.
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