Analyte Specific Reagent. Analytical and performance characteristics are not established.
- Clone
- Ber-ACT8
- Workshop
- V A067
- Other Names
- Integrin alpha E (ITGAE)
- Isotype
- Mouse IgG1, κ
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
984806 | 500 µL | $249 |
CD103 is a type I transmembrane glycoprotein also known as αE integrin, integrin αIEL chain, and human mucosal lymphocyte antigen 1. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. Treg cells express high level of CD103. Hairy cell leukemia has also been shown to express CD103. The expression of CD103 on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as an αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
Product DetailsProduct Details
- Reactivity
- Human
- Formulation
- Phosphate-buffered solution, pH7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- 50 µg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
Suggested for Flow Cytometry
- Disclaimer
-
WARNINGS AND PRECAUTIONS
- Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
- This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
- All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
- Do not use this reagent beyond the expiration date stated on the label.
- Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
- Avoid prolonged exposure of the reagent or stained cells to light.
Antigen Details
- Antigen References
-
- Parker CM, et al. 1992. Proc Natl Acad Sci USA. 89:1924-8.
- Kruschwitz M, et al. 1991. J Clin Pathol. 44:636-45.
- Schon MP, et al. 1999. J Immunol. 162:6641-9.
- Shaw SK, et al. 1994. J Biol Chem. 269:6016-25.
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD103 (Integrin αE)
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FITC anti-human CD103 (Integrin αE)
PHA-stimulated (3 day) human peripheral blood mononuclear ce... PHA-stimulated (3 day) human peripheral blood lymphocytes st... -
PE anti-human CD103 (Integrin αE)
PHA-stimulated (3 day) human peripheral blood lymphocytes st... -
Alexa Fluor® 488 anti-human CD103 (Integrin αE)
PHA-stimulated (3 day) human peripheral blood lymphocytes st... Human peripheral blood lymphocytes stained with mouse IgG1, ... -
Alexa Fluor® 647 anti-human CD103 (Integrin αE)
PHA-stimulated (3day) human peripheral blood mononuclear cel... Human peripheral blood mononuclear cells stained with mouse ... -
PE/Cyanine7 anti-human CD103 (Integrin αE)
-
Brilliant Violet 421™ anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood lymphocytes s... -
APC anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood lymphocytes w... -
Brilliant Violet 605™ anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood lymphocytes w... -
Biotin anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood lymphocytes w... -
Brilliant Violet 711™ anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood lymphocytes w... -
PE/Dazzle™ 594 anti-human CD103 (Integrin αE)
PHA-stimulated (3day) human peripheral blood mononuclear cel... -
PerCP/Cyanine5.5 anti-human CD103 (Integrin αE)
PHA-stimulated (3 day) human peripheral blood mononuclear ce... -
Brilliant Violet 785™ anti-human CD103 (Integrin αE)
PHA-stimulated (3 day) human peripheral blood lymphocytes st... -
APC/Cyanine7 anti-human CD103 (Integrin αE)
PHA-stimulated (3 day) human peripheral blood lymphocytes st... -
TotalSeq™-A0145 anti-human CD103 (Integrin αE)
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TotalSeq™-C0145 anti-human CD103 (Integrin αE)
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TotalSeq™-B0145 anti-human CD103 (Integrin αE)
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APC/Fire™ 750 anti-human CD103 (Integrin αE)
PHA-stimulated (3 day) human peripheral blood lymphocytes we... -
PE/Fire™ 700 anti-human CD103 (Integrin αE) Antibody
PHA-stimulated (3 days) human peripheral blood lymphocytes s... -
TotalSeq™-D0145 anti-human CD103 (Integrin αE)
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PE/Fire™ 640 anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood lymphocytes s... -
PE anti-human CD103
Typical result of PHA-stimulated (3 days) human peripheral b... -
FITC anti-human CD103
Typical results from PHA-stimulated (3 days) human periphera... -
APC anti-human CD103
Typical results from PHA-stimulated (3 days) human periphera... -
Spark YG™ 581 anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood mononuclear c... -
Spark NIR™ 685 anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood mononuclear c... -
Spark Blue™ 550 anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood mononuclear c... -
PE/Fire™ 810 anti-human CD103 (Integrin αE)
PHA-stimulated (3 days) human peripheral blood mononuclear c... -
GMP FITC anti-human CD103 (Integrin αE)
Typical result of PHA-stimulated (3 days) human peripheral b... -
GMP PE anti-human CD103 (Integrin αE)
Typical result of PHA-stimulated (3 days) human peripheral b... -
Spark Red™ 718 anti-human CD103 (Integrin αE) (Flexi-Fluor™)
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Spark Blue™ 574 anti-human CD103 (Integrin αE) (Flexi-Fluor™)
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