FITC anti-mouse/human CD44 Recombinant Antibody, CD44, QA19A43

Pricing & Availability

Clone: QA19A43 (See other available formats)
Regulatory Status: RUO
Other Names: Hermes, Pgp1, H-CAM, or HUTCH
Isotype: Rat IgG2a, κ
Ave. Rating: Submit a Review
Product Citations: publications

C57BL/6 splenocytes were stained with anti-mouse/human CD44 recombinant (clone QA19A43) FITC (filled histogram) or rat IgG2a, κ FITC isotype control (open histogram).

Compare all formats See FITC spectral data

Cat #

Size

Price

Quantity Check Availability

Save

163605

25 µg

$83

Check Availability

Need larger quantities of this item?
Request Bulk Quote

163606

100 µg

$188

Check Availability

Need larger quantities of this item?
Request Bulk Quote

Description

CD44 is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Mouse, Human
Antibody Type: Recombinant
Host Species: Rat
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2894435 (BioLegend Cat. No. 163605)
AB_2894435 (BioLegend Cat. No. 163606)

Antigen Details

Structure: Variable splicing of CD44 gene generates many CD44 isoforms, 80-95 kD
Distribution: All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells.
Function: Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM.
Ligand/Receptor: Hyaluronan, MIP-1β, fibronectin, collagen.
Antigen References: Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.

Haynes BF, et al. 1991. Cancer Cells. 3:347.

Goldstein LA, et al. 1989. Cell. 56:1063.

Mikecz K, et al. 1995. Nat Med. 1:558.

Hegde V, et al. 2008. J Leukocyte Biol. 84:134.

Liu T, et al. 2009. Biol Direct. 4:40.
Gene ID: 12505 View all products for this Gene ID
UniProt: View information about CD44 on UniProt.org

Documentation

Reviews

Review This Product

Related Protocols

Cell Surface Flow Cytometry Staining Protocol

Related Products

Description	Clone	Applications

Related Pages & Pathways

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD44 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse/human CD44 Recombinant Antibody	QA19A43	FC
PE/Cyanine7 anti-mouse/human CD44 Recombinant	QA19A43	FC
APC anti-mouse/human CD44 Recombinant Antibody	QA19A43	FC
FITC anti-mouse/human CD44 Recombinant Antibody	QA19A43	FC
PE anti-mouse/human CD44 Recombinant Antibody	QA19A43	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 09/02/2021

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.